Recombinant multi-species PPM1F/ CAMKP/ CaMKPase protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PPM1F protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: PPM1F, gene name: PPM1F, also named as CAMKP, CaMKPase, FEM-2, POPX2, hFEM-2. The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined. [provided by RefSeq, Jul 2008].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP2664-Ag-1Human PPM1F proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP2664-Ag-1Rat PPM1F proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP2664-Ag-1Mouse PPM1F proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP2664-Ag-1Cynomolgus/ Rhesus macaque PPM1F proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP2664-Ag-1Feline PPM1F proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP2664-Ag-1Canine PPM1F proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP2664-Ag-1Bovine PPM1F proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP2664-Ag-1Equine PPM1F proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-IP2664-Ag, GM-Tg-rg-IP2664-Ag, GM-Tg-mg-IP2664-Ag, GM-Tg-cynog-IP2664-Ag,
GM-Tg-felg-IP2664-Ag, GM-Tg-cang-IP2664-Ag, GM-Tg-bovg-IP2664-Ag, GM-Tg-equg-IP2664-Ag-1
Products Name PPM1F protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NamePPM1F
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PPM1F protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.