Recombinant multi-species FILA2/ FLG2/ IFPS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to FLG2/FLG2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FLG2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: FLG2, gene name: FLG2, also named as IFPS, PSS6. The filaggrin-like protein encoded by this gene is upregulated by calcium, proteolyzed by calpain 1, and is involved in epithelial homeostasis. The encoded protein is required for proper cornification in skin, with defects in this gene being associated with skin diseases. This protein also has a function in skin barrier protection. In fact, in addition to providing a physical barrier, C-terminal fragments of this protein display antimicrobial activity against P. aeruginosa and E. coli. [provided by RefSeq, Jul 2020].

Order information


* GeneMedi provides NON-PROFIT PRICE to support Academic research.Please click inquiry for product quotation. → Inquiry

Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-SE0223-Ag-1Human FLG2 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-SE0223-Ag-1Rat FLG2 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-SE0223-Ag-1Mouse FLG2 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-SE0223-Ag-1Cynomolgus/ Rhesus macaque FLG2 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-SE0223-Ag-1Feline FLG2 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-SE0223-Ag-1Canine FLG2 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE0223-Ag-1Bovine FLG2 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE0223-Ag-1Equine FLG2 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-SE0223-Ag, GM-Tg-rg-SE0223-Ag, GM-Tg-mg-SE0223-Ag, GM-Tg-cynog-SE0223-Ag,
GM-Tg-felg-SE0223-Ag, GM-Tg-cang-SE0223-Ag, GM-Tg-bovg-SE0223-Ag, GM-Tg-equg-SE0223-Ag-1
Products Name FLG2 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameFLG2
Protein Sub-locationSecreted Protein/Potential Cytokines
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FLG2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.