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Recombinant multi-species COMP/ EDM1/ EPD1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Go to COMP/COMP products collection >>Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine COMP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The target: COMP, gene name: COMP, also named as EDM1, EPD1, MED, PSACH, THBS5, TSP5. The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2016].
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| Catalog No. | Product Name | Species | Size | Price |
| GM-Tg-hg-SE0809-Ag-1 | Human COMP protein | Human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-SE0809-Ag-1 | Rat COMP protein | Rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-SE0809-Ag-1 | Mouse COMP protein | Mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-SE0809-Ag-1 | Cynomolgus/ Rhesus macaque COMP protein | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-felg-SE0809-Ag-1 | Feline COMP protein | Feline | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cang-SE0809-Ag-1 | Canine COMP protein | Canine | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-bovg-SE0809-Ag-1 | Bovine COMP protein | Bovine | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-bovg-SE0809-Ag-1 | Equine COMP protein | Equine | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
| Catalog No. | GM-Tg-hg-SE0809-Ag, GM-Tg-rg-SE0809-Ag, GM-Tg-mg-SE0809-Ag, GM-Tg-cynog-SE0809-Ag, GM-Tg-felg-SE0809-Ag, GM-Tg-cang-SE0809-Ag, GM-Tg-bovg-SE0809-Ag, GM-Tg-equg-SE0809-Ag-1 |
| Products Name | COMP protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | COMP |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine COMP protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
