Recombinant multi-species DEF4/ DEFA4/ HNP-4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to DEFA4/DEFA4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DEFA4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: DEFA4, gene name: DEFA4, also named as DEF4, HNP-4, HP-4, HP4. Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production. [provided by RefSeq, Oct 2014].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-SE0852-Ag-1Human DEFA4 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-SE0852-Ag-1Rat DEFA4 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-SE0852-Ag-1Mouse DEFA4 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-SE0852-Ag-1Cynomolgus/ Rhesus macaque DEFA4 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-SE0852-Ag-1Feline DEFA4 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-SE0852-Ag-1Canine DEFA4 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE0852-Ag-1Bovine DEFA4 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE0852-Ag-1Equine DEFA4 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-SE0852-Ag, GM-Tg-rg-SE0852-Ag, GM-Tg-mg-SE0852-Ag, GM-Tg-cynog-SE0852-Ag,
GM-Tg-felg-SE0852-Ag, GM-Tg-cang-SE0852-Ag, GM-Tg-bovg-SE0852-Ag, GM-Tg-equg-SE0852-Ag-1
Products Name DEFA4 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameDEFA4
Protein Sub-locationSecreted Protein/Potential Cytokines
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DEFA4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.