Recombinant multi-species LGI1/ ADLTE/ ADPAEF protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to LGI1/LGI1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LGI1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: LGI1, gene name: LGI1, also named as ADLTE, ADPAEF, ADPEAF, EPITEMPIN, EPT, ETL1, IB1099. This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-SE1069-Ag-1Human LGI1 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-SE1069-Ag-1Rat LGI1 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-SE1069-Ag-1Mouse LGI1 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-SE1069-Ag-1Cynomolgus/ Rhesus macaque LGI1 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-SE1069-Ag-1Feline LGI1 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-SE1069-Ag-1Canine LGI1 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE1069-Ag-1Bovine LGI1 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-SE1069-Ag-1Equine LGI1 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-SE1069-Ag, GM-Tg-rg-SE1069-Ag, GM-Tg-mg-SE1069-Ag, GM-Tg-cynog-SE1069-Ag,
GM-Tg-felg-SE1069-Ag, GM-Tg-cang-SE1069-Ag, GM-Tg-bovg-SE1069-Ag, GM-Tg-equg-SE1069-Ag-1
Products Name LGI1 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameLGI1
Protein Sub-locationSecreted Protein/Potential Cytokines
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LGI1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.