Recombinant multi-species KCRU/ CKMT1B/ CKMT protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CKMT1B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: CKMT1B, gene name: CKMT1B, also named as CKMT, CKMT1, UMTCK. Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins. [provided by RefSeq, Jul 2008].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-SE1393-Ag-1	Human CKMT1B protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-SE1393-Ag-1	Rat CKMT1B protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-SE1393-Ag-1	Mouse CKMT1B protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-SE1393-Ag-1	Cynomolgus/ Rhesus macaque CKMT1B protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-SE1393-Ag-1	Feline CKMT1B protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-SE1393-Ag-1	Canine CKMT1B protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-SE1393-Ag-1	Bovine CKMT1B protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-SE1393-Ag-1	Equine CKMT1B protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-SE1393-Ag, GM-Tg-rg-SE1393-Ag, GM-Tg-mg-SE1393-Ag, GM-Tg-cynog-SE1393-Ag, GM-Tg-felg-SE1393-Ag, GM-Tg-cang-SE1393-Ag, GM-Tg-bovg-SE1393-Ag, GM-Tg-equg-SE1393-Ag-1
Products Name	CKMT1B protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	CKMT1B
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CKMT1B protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.