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Recombinant multi-species PHF8/ JHDM1F/ KDM7B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Go to PHF8/PHF8 products collection >>Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PHF8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The target: PHF8, gene name: PHF8, also named as JHDM1F, KDM7B, MRXSSD, ZNF422. The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. The protein has an N-terminal PHD finger and a central Jumonji C domain. This gene is thought to function as a transcription activator. Defects in this gene are a cause of syndromic X-linked Siderius type intellectual disability (MRXSSD) and over-expression of this gene is associated with several forms of cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017].
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| Catalog No. | Product Name | Species | Size | Price |
| GM-Tg-hg-T00933-Ag-1 | Human PHF8 protein | Human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T00933-Ag-1 | Rat PHF8 protein | Rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T00933-Ag-1 | Mouse PHF8 protein | Mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T00933-Ag-1 | Cynomolgus/ Rhesus macaque PHF8 protein | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-felg-T00933-Ag-1 | Feline PHF8 protein | Feline | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cang-T00933-Ag-1 | Canine PHF8 protein | Canine | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-bovg-T00933-Ag-1 | Bovine PHF8 protein | Bovine | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-bovg-T00933-Ag-1 | Equine PHF8 protein | Equine | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
| Catalog No. | GM-Tg-hg-T00933-Ag, GM-Tg-rg-T00933-Ag, GM-Tg-mg-T00933-Ag, GM-Tg-cynog-T00933-Ag, GM-Tg-felg-T00933-Ag, GM-Tg-cang-T00933-Ag, GM-Tg-bovg-T00933-Ag, GM-Tg-equg-T00933-Ag-1 |
| Products Name | PHF8 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | PHF8 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PHF8 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
