Recombinant multi-species XPO2/ CSE1L/ CAS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CSE1L protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: CSE1L, gene name: CSE1L, also named as CAS, CSE1, XPO2. Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T05324-Ag-1Human CSE1L proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T05324-Ag-1Rat CSE1L proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T05324-Ag-1Mouse CSE1L proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T05324-Ag-1Cynomolgus/ Rhesus macaque CSE1L proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T05324-Ag-1Feline CSE1L proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T05324-Ag-1Canine CSE1L proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T05324-Ag-1Bovine CSE1L proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T05324-Ag-1Equine CSE1L proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-T05324-Ag, GM-Tg-rg-T05324-Ag, GM-Tg-mg-T05324-Ag, GM-Tg-cynog-T05324-Ag,
GM-Tg-felg-T05324-Ag, GM-Tg-cang-T05324-Ag, GM-Tg-bovg-T05324-Ag, GM-Tg-equg-T05324-Ag-1
Products Name CSE1L protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameCSE1L
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CSE1L protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.