Recombinant multi-species CDK8/ K35 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to CDK8/CDK8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CDK8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: CDK8, gene name: CDK8, also named as K35. This gene encodes a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit, cyclin C, are components of the Mediator transcriptional regulatory complex, involved in both transcriptional activation and repression by phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II. This kinase regulates transcription by targeting the cyclin-dependent kinase 7 subunits of the general transcription initiation factor IIH, thus providing a link between the Mediator complex and the basal transcription machinery. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T10822-Ag-1Human CDK8 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T10822-Ag-1Rat CDK8 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T10822-Ag-1Mouse CDK8 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T10822-Ag-1Cynomolgus/ Rhesus macaque CDK8 proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T10822-Ag-1Feline CDK8 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T10822-Ag-1Canine CDK8 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T10822-Ag-1Bovine CDK8 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T10822-Ag-1Equine CDK8 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-T10822-Ag, GM-Tg-rg-T10822-Ag, GM-Tg-mg-T10822-Ag, GM-Tg-cynog-T10822-Ag,
GM-Tg-felg-T10822-Ag, GM-Tg-cang-T10822-Ag, GM-Tg-bovg-T10822-Ag, GM-Tg-equg-T10822-Ag-1
Products Name CDK8 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameCDK8
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CDK8 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
FormulationSupplied as a 0.2 μM filtered solution of PBS, PH7.4.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.