Recombinant multi-species SIR1/ SIRT1/ SIR2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SIRT1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: SIRT1, gene name: SIRT1, also named as SIR2, SIR2L1, SIR2alpha. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T14731-Ag-1	Human SIRT1 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T14731-Ag-1	Rat SIRT1 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T14731-Ag-1	Mouse SIRT1 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T14731-Ag-1	Cynomolgus/ Rhesus macaque SIRT1 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T14731-Ag-1	Feline SIRT1 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T14731-Ag-1	Canine SIRT1 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T14731-Ag-1	Bovine SIRT1 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T14731-Ag-1	Equine SIRT1 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T14731-Ag, GM-Tg-rg-T14731-Ag, GM-Tg-mg-T14731-Ag, GM-Tg-cynog-T14731-Ag, GM-Tg-felg-T14731-Ag, GM-Tg-cang-T14731-Ag, GM-Tg-bovg-T14731-Ag, GM-Tg-equg-T14731-Ag-1
Products Name	SIRT1 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	SIRT1
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SIRT1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.