Recombinant multi-species LEPR/ CD295/ LEP-RD protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LEPR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: LEPR, gene name: LEPR, also named as CD295, LEP-RD, OB-R, OBR, LEPR. The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010].

Order information

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T17163-Ag-1	Human LEPR protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T17163-Ag-1	Rat LEPR protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T17163-Ag-1	Mouse LEPR protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T17163-Ag-1	Cynomolgus/ Rhesus macaque LEPR protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T17163-Ag-1	Feline LEPR protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T17163-Ag-1	Canine LEPR protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T17163-Ag-1	Bovine LEPR protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T17163-Ag-1	Equine LEPR protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T17163-Ag, GM-Tg-rg-T17163-Ag, GM-Tg-mg-T17163-Ag, GM-Tg-cynog-T17163-Ag, GM-Tg-felg-T17163-Ag, GM-Tg-cang-T17163-Ag, GM-Tg-bovg-T17163-Ag, GM-Tg-equg-T17163-Ag-1
Products Name	LEPR protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	LEPR
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LEPR protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.