Recombinant multi-species HNMT/ HMT-S1/ HNMT-S2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HNMT protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: HNMT, gene name: HNMT, also named as HMT-S1, HNMT-S2, MRT51, HNMT. In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008].

Order information

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T17448-Ag-1	Human HNMT protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T17448-Ag-1	Rat HNMT protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T17448-Ag-1	Mouse HNMT protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T17448-Ag-1	Cynomolgus/ Rhesus macaque HNMT protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T17448-Ag-1	Feline HNMT protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T17448-Ag-1	Canine HNMT protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T17448-Ag-1	Bovine HNMT protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T17448-Ag-1	Equine HNMT protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T17448-Ag, GM-Tg-rg-T17448-Ag, GM-Tg-mg-T17448-Ag, GM-Tg-cynog-T17448-Ag, GM-Tg-felg-T17448-Ag, GM-Tg-cang-T17448-Ag, GM-Tg-bovg-T17448-Ag, GM-Tg-equg-T17448-Ag-1
Products Name	HNMT protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	HNMT
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HNMT protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.