Recombinant multi-species ATF4/ ATF-4/ CREB-2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ATF-4/ATF4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: ATF-4, gene name: ATF4, also named as CREB-2, CREB2, TAXREB67, TXREB. This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. [provided by RefSeq, Sep 2011].

Order information

* GeneMedi provides NON-PROFIT PRICE to support Academic research.Please click inquiry for product quotation. → Inquiry

Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T53270-Ag-1	Human ATF-4/ATF4 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T53270-Ag-1	Rat ATF-4/ATF4 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T53270-Ag-1	Mouse ATF-4/ATF4 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T53270-Ag-1	Cynomolgus/ Rhesus macaque ATF-4/ATF4 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T53270-Ag-1	Feline ATF-4/ATF4 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T53270-Ag-1	Canine ATF-4/ATF4 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T53270-Ag-1	Bovine ATF-4/ATF4 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T53270-Ag-1	Equine ATF-4/ATF4 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T53270-Ag, GM-Tg-rg-T53270-Ag, GM-Tg-mg-T53270-Ag, GM-Tg-cynog-T53270-Ag, GM-Tg-felg-T53270-Ag, GM-Tg-cang-T53270-Ag, GM-Tg-bovg-T53270-Ag, GM-Tg-equg-T53270-Ag-1
Products Name	ATF-4/ATF4 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	ATF-4
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ATF-4/ATF4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.