Recombinant multi-species CDK7/ CAK/ CAK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CDK7 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: CDK7, gene name: CDK7, also named as CAK, CAK1, CDKN7, HCAK, MO15, STK1, p39MO15. The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T58449-Ag-1Human CDK7 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T58449-Ag-1Rat CDK7 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T58449-Ag-1Mouse CDK7 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T58449-Ag-1Cynomolgus/ Rhesus macaque CDK7 proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T58449-Ag-1Feline CDK7 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T58449-Ag-1Canine CDK7 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T58449-Ag-1Bovine CDK7 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T58449-Ag-1Equine CDK7 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-T58449-Ag, GM-Tg-rg-T58449-Ag, GM-Tg-mg-T58449-Ag, GM-Tg-cynog-T58449-Ag,
GM-Tg-felg-T58449-Ag, GM-Tg-cang-T58449-Ag, GM-Tg-bovg-T58449-Ag, GM-Tg-equg-T58449-Ag-1
Products Name CDK7 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameCDK7
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CDK7 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.