Recombinant multi-species RASK/ KRAS G12C/ KRAS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KRAS G12C/KRAS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: KRAS G12C, gene name: KRAS, also named as C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, K-Ras, KI-RAS1, KRAS2, NS, NS3, RALD, RASK2, c-Ki-ras2, KRAS. This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008].

Order information

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T59480-Ag-1	Human KRAS G12C/KRAS protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T59480-Ag-1	Rat KRAS G12C/KRAS protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T59480-Ag-1	Mouse KRAS G12C/KRAS protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T59480-Ag-1	Cynomolgus/ Rhesus macaque KRAS G12C/KRAS protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T59480-Ag-1	Feline KRAS G12C/KRAS protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T59480-Ag-1	Canine KRAS G12C/KRAS protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T59480-Ag-1	Bovine KRAS G12C/KRAS protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T59480-Ag-1	Equine KRAS G12C/KRAS protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T59480-Ag, GM-Tg-rg-T59480-Ag, GM-Tg-mg-T59480-Ag, GM-Tg-cynog-T59480-Ag, GM-Tg-felg-T59480-Ag, GM-Tg-cang-T59480-Ag, GM-Tg-bovg-T59480-Ag, GM-Tg-equg-T59480-Ag-1
Products Name	KRAS G12C/KRAS protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	KRAS G12C
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KRAS G12C/KRAS protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.