Recombinant multi-species TLR3/ CD283/ IIAE2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TLR3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: TLR3, gene name: TLR3, also named as CD283, IIAE2. The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It thus plays a role in host defense against multiple viruses. [provided by RefSeq, Jul 2021].

Order information

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T67894-Ag-1	Human TLR3 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T67894-Ag-1	Rat TLR3 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T67894-Ag-1	Mouse TLR3 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T67894-Ag-1	Cynomolgus/ Rhesus macaque TLR3 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T67894-Ag-1	Feline TLR3 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T67894-Ag-1	Canine TLR3 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T67894-Ag-1	Bovine TLR3 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T67894-Ag-1	Equine TLR3 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T67894-Ag, GM-Tg-rg-T67894-Ag, GM-Tg-mg-T67894-Ag, GM-Tg-cynog-T67894-Ag, GM-Tg-felg-T67894-Ag, GM-Tg-cang-T67894-Ag, GM-Tg-bovg-T67894-Ag, GM-Tg-equg-T67894-Ag-1
Products Name	TLR3 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	TLR3
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TLR3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.