Recombinant multi-species MTOR/ mTOR/ FRAP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine mTOR/MTOR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: mTOR, gene name: MTOR, also named as FRAP, FRAP1, FRAP2, RAFT1, RAPT1, SKS. The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This kinase is a component of two distinct complexes, mTORC1, which controls protein synthesis, cell growth and proliferation, and mTORC2, which is a regulator of the actin cytoskeleton, and promotes cell survival and cell cycle progression. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. Inhibitors of mTOR are used in organ transplants as immunosuppressants, and are being evaluated for their therapeutic potential in SARS-CoV-2 infections. Mutations in this gene are associated with Smith-Kingsmore syndrome and somatic focal cortical dysplasia type II. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Aug 2020].

Order information

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T75243-Ag-1	Human mTOR/MTOR protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T75243-Ag-1	Rat mTOR/MTOR protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T75243-Ag-1	Mouse mTOR/MTOR protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T75243-Ag-1	Cynomolgus/ Rhesus macaque mTOR/MTOR protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T75243-Ag-1	Feline mTOR/MTOR protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T75243-Ag-1	Canine mTOR/MTOR protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T75243-Ag-1	Bovine mTOR/MTOR protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T75243-Ag-1	Equine mTOR/MTOR protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T75243-Ag, GM-Tg-rg-T75243-Ag, GM-Tg-mg-T75243-Ag, GM-Tg-cynog-T75243-Ag, GM-Tg-felg-T75243-Ag, GM-Tg-cang-T75243-Ag, GM-Tg-bovg-T75243-Ag, GM-Tg-equg-T75243-Ag-1
Products Name	mTOR/MTOR protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	mTOR
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine mTOR/MTOR protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.