Recombinant multi-species FPPS/ FDPS/ FPS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FDPS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: FDPS, gene name: FDPS, also named as FPPS, FPS, POROK9. This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008].

Order information

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T86528-Ag-1	Human FDPS protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T86528-Ag-1	Rat FDPS protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T86528-Ag-1	Mouse FDPS protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T86528-Ag-1	Cynomolgus/ Rhesus macaque FDPS protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T86528-Ag-1	Feline FDPS protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T86528-Ag-1	Canine FDPS protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T86528-Ag-1	Bovine FDPS protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T86528-Ag-1	Equine FDPS protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T86528-Ag, GM-Tg-rg-T86528-Ag, GM-Tg-mg-T86528-Ag, GM-Tg-cynog-T86528-Ag, GM-Tg-felg-T86528-Ag, GM-Tg-cang-T86528-Ag, GM-Tg-bovg-T86528-Ag, GM-Tg-equg-T86528-Ag-1
Products Name	FDPS protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	FDPS
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FDPS protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.