Recombinant multi-species IL24/ C49A/ FISP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL24 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: IL24, gene name: IL24, also named as C49A, FISP, IL10B, MDA7, MOB5, ST16. This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T93450-Ag-1	Human IL24 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T93450-Ag-1	Rat IL24 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T93450-Ag-1	Mouse IL24 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T93450-Ag-1	Cynomolgus/ Rhesus macaque IL24 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T93450-Ag-1	Feline IL24 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T93450-Ag-1	Canine IL24 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T93450-Ag-1	Bovine IL24 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T93450-Ag-1	Equine IL24 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T93450-Ag, GM-Tg-rg-T93450-Ag, GM-Tg-mg-T93450-Ag, GM-Tg-cynog-T93450-Ag, GM-Tg-felg-T93450-Ag, GM-Tg-cang-T93450-Ag, GM-Tg-bovg-T93450-Ag, GM-Tg-equg-T93450-Ag-1
Products Name	IL24 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	IL24
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL24 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.