Recombinant multi-species ATS5/ ADAMTS5/ ADAM-TS 11 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ADAMTS5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: ADAMTS5, gene name: ADAMTS5, also named as ADAM-TS 11, ADAM-TS 5, ADAM-TS5, ADAMTS-11, ADAMTS-5, ADAMTS11, ADMP-2. This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis. [provided by RefSeq, Feb 2016].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T98896-Ag-1	Human ADAMTS5 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T98896-Ag-1	Rat ADAMTS5 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T98896-Ag-1	Mouse ADAMTS5 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T98896-Ag-1	Cynomolgus/ Rhesus macaque ADAMTS5 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T98896-Ag-1	Feline ADAMTS5 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T98896-Ag-1	Canine ADAMTS5 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T98896-Ag-1	Bovine ADAMTS5 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T98896-Ag-1	Equine ADAMTS5 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T98896-Ag, GM-Tg-rg-T98896-Ag, GM-Tg-mg-T98896-Ag, GM-Tg-cynog-T98896-Ag, GM-Tg-felg-T98896-Ag, GM-Tg-cang-T98896-Ag, GM-Tg-bovg-T98896-Ag, GM-Tg-equg-T98896-Ag-1
Products Name	ADAMTS5 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	ADAMTS5
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ADAMTS5 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.