Bovine hemoglobin antibody and antigen (recombinant protein)

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Diagnostic anti-Bovine hemoglobin antibodies pairs and antigen for animal health (animal Bovines/Cattle Anemia) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product Description

Reference

Validation Data

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Target/Biomarker Information

Hemoglobin is a vital protein present in the red blood cells of all mammals, including cattle. In bovines, hemoglobin performs essential functions similar to those in other mammals, carrying oxygen from the lungs to the rest of the body and transporting carbon dioxide from the tissues back to the lungs.

Oxygen Carrying Capacity: Bovine hemoglobin binds oxygen in the lungs and releases it to the tissues. The efficiency of this oxygen transport is crucial for the metabolic activities of the animal, especially in supporting the muscle function necessary for movement and, in dairy cows, for milk production.

Structure: Bovine hemoglobin is a tetramer, like human hemoglobin, consisting of two alpha and two beta chains, each with an iron-containing heme group. This structure is highly efficient for oxygen binding and release.

Normal Levels: The normal range for hemoglobin in cattle varies but generally falls between 8 to 15 g/dL. It's important for these levels to be maintained for the animals to remain healthy and productive.

Anemia in Cattle: Low levels of hemoglobin in cattle, known as anemia, can result from various conditions, including nutritional deficiencies (such as iron, vitamin B12, or folate), blood loss (due to parasites or injury), or diseases that affect red blood cell production or increase their destruction.

Polycythemia: Elevated hemoglobin levels, although less common, can occur in situations where there is polycythemia, an increased concentration of red blood cells. This condition can be due to dehydration, which concentrates the blood, or less commonly, due to bone marrow disorders.

Diagnostic Significance: Hemoglobin measurement is a standard part of the complete blood count (CBC) and is used to diagnose and monitor various health conditions in cattle. It is also used to assess the oxygen-carrying capacity of the blood, which can be important in managing animal health and detecting disease.

Hemoglobinopathies: While less documented than in humans, cattle can have genetic variations in hemoglobin, though the clinical significance of these variations in cattle is not as well characterized.

Impact on Productivity: Hemoglobin levels can have direct implications for the productivity of cattle. Adequate oxygenation is necessary for the metabolic demands of growth, reproduction, and lactation. Hence, monitoring and maintaining optimal hemoglobin levels are important for the overall productivity of the herd.

In summary, bovine hemoglobin plays a fundamental role in the physiology of cattle, with its primary functions being the transport of oxygen and carbon dioxide critical to the metabolic processes of the animal. Maintaining the appropriate levels of hemoglobin is essential for the health and productivity of cattle, and it is a key parameter measured in veterinary medicine to assess and monitor the health status of these animals.

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