Canine hemoglobin antibody and antigen (recombinant protein)

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Diagnostic anti-Canine hemoglobin antibodies pairs and antigen for animal health (animal Dog/Canine Anemia) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-Hemoglobin-Ag01	Canine hemoglobin	$3090.00
GMP-CAN-Hemoglobin-Ab01	Anti-Canine hemoglobin mouse monoclonal antibody (mAb)	$3090.00
GMP-CAN-Hemoglobin-Ab02	Anti-Canine hemoglobin mouse monoclonal antibody (mAb)	$3090.00
GMP-CAN-Hemoglobin-Ab03	Anti-Canine hemoglobin human monoclonal antibody (mAb)	$3090.00
GMP-CAN-Hemoglobin-Ab04	Anti-Canine hemoglobin human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-CAN-Hemoglobin-Ag01
Product Name	Canine hemoglobin
Target/Biomarker	Canine hemoglobin
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine hemoglobin antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Canine hemoglobin level test of animal Dog/Canine with Anemia.
Tag	His
Reconized/Reactive Specics	Canine hemoglobin
Product description	Recombinant Canine hemoglobin protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-CAN-Hemoglobin-Ab01,GMP-CAN-Hemoglobin-Ab02
Target/Biomarker	Canine hemoglobin
Product Name	Anti-Canine hemoglobin mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine hemoglobin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine hemoglobin antibodies in Canine hemoglobin level test of animal Dog/Canine with Anemia.
Product description	Anti-Canine hemoglobin mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine hemoglobin antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-CAN-Hemoglobin-Ab03,GMP-CAN-Hemoglobin-Ab04
Target/Biomarker	Canine hemoglobin
Product Name	Anti-Canine hemoglobin human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Canine hemoglobin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine hemoglobin antibodies in Canine hemoglobin level test of animal Dog/Canine with Anemia.
Product description	Anti-Canine hemoglobin mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker Information

Canine Pancreatic Lipase (cPL) emerges as a linchpin in the intricate tapestry of canine digestive physiology. This vital enzyme is secreted by the exocrine pancreas in response to dietary fat intake, facilitating the digestion and absorption of lipids in the small intestine. Structurally, cPL is a glycoprotein, characterized by its enzymatic active site, where the magic of lipid hydrolysis unfolds.

The enzymatic function of cPL is of paramount importance in lipid metabolism. When dietary fats, in the form of triglycerides, enter the small intestine, they undergo emulsification, thanks to the action of bile salts. Subsequently, cPL steps onto the stage, catalyzing the hydrolysis of triglycerides into their constituent parts: fatty acids and glycerol. These breakdown products are then absorbed through the intestinal mucosa, embarking on a journey through the lymphatic system to reach various tissues throughout the body.

Beyond its role in nutrient absorption, cPL has implications in the regulation of fat storage and utilization. It is part of a finely tuned system that ensures the availability of energy-rich fatty acids for immediate use or storage in adipose tissue. This mechanism is central to a dog's overall metabolic health and energy balance., The measurement of Canine Pancreatic Lipase (cPL) levels extends far beyond the realm of routine diagnostics; it serves as a beacon guiding veterinarians through the complex landscape of canine pancreatic health, offering invaluable insights into a dog's well-being.

Pancreatitis, characterized by inflammation of the pancreas, is a pervasive and potentially severe condition in dogs. Elevated cPL levels are indicative of pancreatitis, which can range in severity from mild, self-limiting forms to acute, life-threatening episodes. Accurate diagnosis through cPL measurement is instrumental in initiating prompt and appropriate treatment, a crucial factor in improving the prognosis for affected dogs.

The utility of cPL measurement doesn't stop at diagnosis. It plays a pivotal role in monitoring the progression of pancreatitis and evaluating the response to therapeutic interventions. By tracking cPL levels over time, veterinarians can fine-tune treatment plans, optimizing the care provided to each canine patient.

Furthermore, cPL measurement serves as a differentiating tool, aiding in the classification of pancreatitis into acute and chronic forms. Acute pancreatitis typically presents with sudden, severe inflammation, while chronic pancreatitis is characterized by recurrent or long-term inflammation. Accurate classification is vital for tailoring treatment strategies to the specific needs of each patient.

In cases where pancreatitis is suspected but not yet clinically evident, measuring cPL levels can serve as an early warning system. Detecting elevated cPL levels in asymptomatic dogs can prompt further investigation and preemptive measures to prevent the onset of more severe pancreatitis.

Additionally, cPL measurement plays a role in monitoring canine patients with chronic pancreatic conditions, such as exocrine pancreatic insufficiency (EPI). EPI is characterized by the inadequate secretion of digestive enzymes, including cPL, leading to malabsorption of nutrients. Regular monitoring of cPL levels is instrumental in managing EPI and ensuring affected dogs receive the necessary enzyme replacement therapy.

In summary, the measurement of Canine Pancreatic Lipase (cPL) is a versatile and indispensable tool in the realm of veterinary medicine. Its clinical applications span from the diagnosis and monitoring of pancreatitis to the differentiation of acute and chronic forms of the condition. Furthermore, cPL measurement serves as a sentinel, offering early detection and intervention in potential cases, ultimately contributing to the enhanced well-being and longevity of our canine companions.

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