Equine Dig antibody and antigen (recombinant protein)

Diagnostic anti-Equine Dig antibodies pairs and antigen for animal health (animal Equine/Horse) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Equine disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-EQU-Dig-Ag01Equine Dig$3090.00
GMP-EQU-Dig-Ab01Anti-Equine Dig mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-Dig-Ab02Anti-Equine Dig mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-Dig-Ab03Anti-Equine Dig human monoclonal antibody (mAb)$3090.00
GMP-EQU-Dig-Ab04Anti-Equine Dig human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-EQU-Dig-Ag01
Product NameEquine Dig
Target/BiomarkerEquine Dig
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Equine Dig antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Dig level test of animal Equine/Horse.
TagHis
Reconized/Reactive SpecicsEquine Dig
Product descriptionRecombinant Equine Dig protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-Dig-Ab01,GMP-EQU-Dig-Ab02
Target/BiomarkerEquine Dig
Product NameAnti-Equine Dig mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Equine Dig antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine Dig antibodies in Equine Dig level test of animal Equine/Horse.
Product descriptionAnti-Equine Dig mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine Dig antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-Dig-Ab03,GMP-EQU-Dig-Ab04
Target/BiomarkerEquine Dig
Product NameAnti-Equine Dig human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Equine Dig antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine Dig antibodies in Equine Dig level test of animal Equine/Horse.
Product descriptionAnti-Equine Dig mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Equine Dig, or the measurement of digoxin levels in horses, holds a pivotal role in equine cardiology. To delve deeper into what it entails, we must understand the significance of digoxin itself. Digoxin is a cardiac glycoside derived from the leaves of the foxglove plant (Digitalis purpurea). Its therapeutic properties in both humans and horses revolve around its ability to enhance the contractility of cardiac muscle fibers while reducing heart rate.

    In the equine world, the measurement of Horse Dig primarily involves quantifying the concentration of digoxin in the horse's circulatory system. It's a meticulous process carried out through immunoassays, allowing veterinarians to gain precise insights into the pharmacokinetics of digoxin within the equine physiology.

    Digoxin operates by inhibiting the sodium-potassium pump in myocardial cells, causing an elevation in intracellular calcium levels. This, in turn, increases the force of myocardial contraction, thereby enhancing the heart's pumping efficiency. Simultaneously, digoxin exerts an anti-arrhythmic effect by reducing the frequency of atrioventricular node firing, especially useful in horses with atrial fibrillation, a condition characterized by irregular heart rhythms.

    Understanding what Equine Dig represents is integral in comprehending its clinical importance. It serves as a window into the status of a horse's cardiovascular health, specifically in the context of digoxin therapy. Digoxin is employed to manage various cardiac conditions in horses, most notably congestive heart failure and atrial fibrillation.



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