Feline C-Peptide antibody and antigen (recombinant protein)

Diagnostic anti-Feline C-Peptide antibodies pairs and antigen for animal health (animal Cat/Feline type 1 diabetes mellitus) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-C-Peptide-Ag01Feline C-Peptide$3090.00
GMP-FEL-C-Peptide-Ab01Anti-Feline C-Peptide mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-C-Peptide-Ab02Anti-Feline C-Peptide mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-C-Peptide-Ab03Anti-Feline C-Peptide human monoclonal antibody (mAb)$3090.00
GMP-FEL-C-Peptide-Ab04Anti-Feline C-Peptide human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-C-Peptide-Ag01
Product NameFeline C-Peptide
Target/BiomarkerFeline C-Peptide
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline C-Peptide antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in C-Peptide level test of animal Cat/Feline with type 1 diabetes mellitus.
TagHis
Reconized/Reactive SpecicsFeline C-Peptide
Product descriptionRecombinant Feline C-Peptide protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-C-Peptide-Ab01,GMP-FEL-C-Peptide-Ab02
Target/BiomarkerFeline C-Peptide
Product NameAnti-Feline C-Peptide mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline C-Peptide antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline C-Peptide antibodies in Feline C-Peptide level test of animal Cat/Feline with type 1 diabetes mellitus.
Product descriptionAnti-Feline C-Peptide mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline C-Peptide antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-C-Peptide-Ab03,GMP-FEL-C-Peptide-Ab04
Target/BiomarkerFeline C-Peptide
Product NameAnti-Feline C-Peptide human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline C-Peptide antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline C-Peptide antibodies in Feline C-Peptide level test of animal Cat/Feline with type 1 diabetes mellitus.
Product descriptionAnti-Feline C-Peptide mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Feline C-Peptide, a remarkable peptide composed of 31 amino acids, is intricately intertwined with the physiological tapestry of cats. It emerges as a critical component of pancreatic function, serving as both a mirror and a marker of endogenous insulin production. C-Peptide is born during the proteolytic cleavage of proinsulin, a precursor to insulin. While insulin takes on the central role in regulating glucose homeostasis, Feline C-Peptide plays a parallel and equally crucial role, co-secreted alongside insulin by the pancreas.

    Feline C-Peptide follows a pulsatile release pattern into the bloodstream, a pattern that mimics the body's natural insulin secretion. This distinctive feature sets it apart from exogenously administered insulin, which delivers a continuous and uniform dose. As C-Peptide levels rise in response to elevated blood glucose levels, it serves as an invaluable indicator of the pancreas's health and its ability to produce insulin.

    Beyond its role as a mirror of insulin secretion, Feline C-Peptide plays an essential role in the diagnosis and differentiation of diabetes in cats. This differentiation is not merely a matter of semantics but a pivotal determinant of treatment approaches. Low or undetectable levels of C-Peptide are typically associated with Type 1 diabetes, which results from the autoimmune destruction of pancreatic beta cells, leading to the absence of endogenous insulin production. In contrast, Type 2 diabetes in cats is characterized by varying C-Peptide levels, reflecting a complex interplay of insulin resistance and impaired insulin secretion. The ability to distinguish between these two forms of diabetes guides veterinarians in selecting the most appropriate therapeutic strategies for their feline patients.



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