Feline G100 antibody and antigen (recombinant protein)

Diagnostic anti-Feline G100 antibodies pairs and antigen for animal health (animal Cat/Feline gastrinoma) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No. Description US $ Price (per mg)
GMP-FEL-G100-Ag01 Recombinant Feline G100 protein 3090
GMP-FEL-G100-Ab01 Anti-Feline G100 mouse monoclonal antibody (mAb) 3090
GMP-FEL-G100-Ab02 Anti-Feline G100 mouse monoclonal antibody (mAb) 3090
GMP-FEL-G100-Ab03 Anti-Feline G100 human monoclonal antibody (mAb) 3090
GMP-FEL-G100-Ab04 Anti-Feline G100 human monoclonal antibody (mAb) 3090

Size: 1mg | 10mg | 100mg



Product Description

Cat No. of Products GMP-FEL-G100-Ag01
Product Name Recombinant Feline G100 protein
Target/Biomarker Feline Gastrin (G100)
Alias of Target/Biomarker Feline Gastrin (G100)
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Feline Gastrin antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in G100 level test of animal Cat/Feline with gastrinoma.
Tag His
Products description Recombinant Feline G100 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products GMP-FEL-G100-Ab01, GMP-FEL-G100-Ab02
Product Name Anti-Feline G100 mouse monoclonal antibody (mAb)
Target/Biomarker Feline Gastrin (G100)
Alias of Target/Biomarker Feline Gastrin (G100)
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Recombinant Feline Gastrin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-G100 antibodies in G100 level test of animal Cat/Feline with gastrinoma.
Tag mFc
Products description Anti-Feline G100 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-G100 antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products GMP-FEL-G100-Ab03, GMP-FEL-G100-Ab04
Product Name Anti-Feline G100 human monoclonal antibody (mAb)
Target/Biomarker Feline Gastrin (G100)
Alias of Target/Biomarker Feline Gastrin (G100)
Expression platform CHO
Isotypes Human IgG1
Bioactivity validation Recombinant Feline Gastrin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-G100 antibodies in G100 level test of animal Cat/Feline with gastrinoma.
Tag hFc
Products description Anti-Feline G100 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-G100 antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker information

    Cat/Feline Gastrin emerges as a remarkable peptide hormone, intricately woven into the tapestry of feline digestion. This hormone is primarily produced by G cells, specialized enteroendocrine cells residing within the gastric mucosa of the cat's stomach and duodenum. The journey of Gastrin commences with the act of feeding. When a cat consumes a meal, especially one rich in proteins, it triggers the release of Gastrin. Gastrin, in turn, exerts its influence on parietal cells located in the stomach lining. These parietal cells are responsible for secreting hydrochloric acid (HCl), a potent digestive enzyme. Gastrin's binding to specific receptors on parietal cells prompts them to increase their production of HCl. The surge in gastric acid serves a pivotal purpose in digestion. It creates an optimal acidic environment within the stomach, crucial for the activation of pepsin, another vital enzyme that participates in protein digestion. Pepsinogen, an inactive form of pepsin, is activated in the acidic milieu of the stomach and plays a central role in breaking down complex proteins into more digestible fragments. The regulation of Gastrin secretion is a sophisticated process, subject to intricate feedback mechanisms. When the pH level in the stomach reaches an appropriately acidic state, it signals the inhibition of Gastrin release. This negative feedback loop prevents excessive acid production, ensuring that the digestive process remains finely tuned to the dietary content and digestive needs of the cat. Gastrin exhibits sensitivity to different dietary components. Certain amino acids, such as phenylalanine and tryptophan, can stimulate Gastrin release. This responsiveness to dietary cues underscores Gastrin's role as a key mediator of digestion, exquisitely attuned to the nutritional composition of the feline diet.



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