Feline G100 antibody and antigen (recombinant protein)

Diagnostic anti-Feline G100 antibodies pairs and antigen for animal health (animal Cat/Feline gastrinoma) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-G100-Ag01Feline G100$3090.00
GMP-FEL-G100-Ab01Anti-Feline G100 mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-G100-Ab02Anti-Feline G100 mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-G100-Ab03Anti-Feline G100 human monoclonal antibody (mAb)$3090.00
GMP-FEL-G100-Ab04Anti-Feline G100 human monoclonal antibody (mAb)$3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-G100-Ag01
Product NameFeline G100
Target/BiomarkerFeline G100
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline G100 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in G100 level test of animal Cat/Feline with gastrinoma.
TagHis
Reconized/Reactive SpecicsFeline G100
Product descriptionRecombinant Feline G100 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-G100-Ab01,GMP-FEL-G100-Ab02
Target/BiomarkerFeline G100
Product NameAnti-Feline G100 mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline G100 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline G100 antibodies in Feline G100 level test of animal Cat/Feline with gastrinoma.
Product descriptionAnti-Feline G100 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline G100 antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-G100-Ab03,GMP-FEL-G100-Ab04
Target/BiomarkerFeline G100
Product NameAnti-Feline G100 human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline G100 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline G100 antibodies in Feline G100 level test of animal Cat/Feline with gastrinoma.
Product descriptionAnti-Feline G100 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Cat/Feline Gastrin emerges as a remarkable peptide hormone, intricately woven into the tapestry of feline digestion. This hormone is primarily produced by G cells, specialized enteroendocrine cells residing within the gastric mucosa of the cat's stomach and duodenum.

    The journey of Gastrin commences with the act of feeding. When a cat consumes a meal, especially one rich in proteins, it triggers the release of Gastrin. Gastrin, in turn, exerts its influence on parietal cells located in the stomach lining. These parietal cells are responsible for secreting hydrochloric acid (HCl), a potent digestive enzyme. Gastrin's binding to specific receptors on parietal cells prompts them to increase their production of HCl.

    The surge in gastric acid serves a pivotal purpose in digestion. It creates an optimal acidic environment within the stomach, crucial for the activation of pepsin, another vital enzyme that participates in protein digestion. Pepsinogen, an inactive form of pepsin, is activated in the acidic milieu of the stomach and plays a central role in breaking down complex proteins into more digestible fragments.

    The regulation of Gastrin secretion is a sophisticated process, subject to intricate feedback mechanisms. When the pH level in the stomach reaches an appropriately acidic state, it signals the inhibition of Gastrin release. This negative feedback loop prevents excessive acid production, ensuring that the digestive process remains finely tuned to the dietary content and digestive needs of the cat.

    Gastrin exhibits sensitivity to different dietary components. Certain amino acids, such as phenylalanine and tryptophan, can stimulate Gastrin release. This responsiveness to dietary cues underscores Gastrin's role as a key mediator of digestion, exquisitely attuned to the nutritional composition of the feline diet.



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