Feline hemoglobin antibody and antigen (recombinant protein)

Diagnostic anti-Feline hemoglobin antibodies pairs and antigen for animal health (animal Cat/Feline Anemia) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-hemoglobin-Ag01Feline hemoglobin$3090.00
GMP-FEL-hemoglobin-Ab01Anti-Feline hemoglobin mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-hemoglobin-Ab02Anti-Feline hemoglobin mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-hemoglobin-Ab03Anti-Feline hemoglobin human monoclonal antibody (mAb)$3090.00
GMP-FEL-hemoglobin-Ab04Anti-Feline hemoglobin human monoclonal antibody (mAb)$3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-hemoglobin-Ag01
Product NameFeline hemoglobin
Target/BiomarkerFeline hemoglobin
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline hemoglobin antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in hemoglobin level test of animal Cat/Feline with Anemia.
TagHis
Reconized/Reactive SpecicsFeline hemoglobin
Product descriptionRecombinant Feline hemoglobin protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-hemoglobin-Ab01,GMP-FEL-hemoglobin-Ab02
Target/BiomarkerFeline hemoglobin
Product NameAnti-Feline hemoglobin mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline hemoglobin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline hemoglobin antibodies in Feline hemoglobin level test of animal Cat/Feline with Anemia.
Product descriptionAnti-Feline hemoglobin mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline hemoglobin antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-hemoglobin-Ab03,GMP-FEL-hemoglobin-Ab04
Target/BiomarkerFeline hemoglobin
Product NameAnti-Feline hemoglobin human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline hemoglobin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline hemoglobin antibodies in Feline hemoglobin level test of animal Cat/Feline with Anemia.
Product descriptionAnti-Feline hemoglobin mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Hemoglobin is a crucial protein found in the red blood cells of all mammals, including cats. In felines, as in other species, hemoglobin's primary function is to transport oxygen from the lungs to the body's tissues and to facilitate the return of carbon dioxide from the tissues back to the lungs for exhalation.

    Here are some key points about feline hemoglobin:

    Oxygen Transport: Each hemoglobin molecule can bind up to four oxygen molecules, allowing for efficient oxygen transport. In cats, hemoglobin binds oxygen in the lungs and releases it in the tissues where the oxygen concentration is lower.

    Carbon Dioxide Transport: Hemoglobin also plays a role in transporting approximately 20% of the carbon dioxide produced by metabolism in tissues back to the lungs, where it is expelled from the body.

    Hemoglobin Structure: Feline hemoglobin, like that of other mammals, is composed of four protein subunits, each containing an iron-containing heme group. The iron within these heme groups is what binds oxygen, and the globin part of the molecule assists in the regulation of oxygen binding and release.

    Hemoglobin Levels: The normal range of hemoglobin in cats can vary, but it typically falls between 9.5 to 16.1 g/dL. It's important for veterinarians to know the normal hemoglobin levels for cats when interpreting blood tests since deviations can indicate various health issues.

    Health Implications: Low hemoglobin levels (anemia) in cats can result from various conditions, including blood loss, hemolysis (destruction of red blood cells), or insufficient red blood cell production. Symptoms of anemia in cats may include lethargy, weakness, pale mucous membranes, and rapid breathing. High hemoglobin levels may be seen in conditions leading to polycythemia, which is an increased concentration of red blood cells in the blood.

    Diagnostic Use: Measuring hemoglobin concentration is a standard part of a complete blood count (CBC) and is critical in diagnosing and monitoring diseases. Veterinarians use hemoglobin levels, along with other red blood cell parameters, to assess a cat's oxygen-carrying capacity and overall health status.

    Hemoglobinopathies: While relatively rare, cats can suffer from hemoglobinopathies—disorders affecting the structure, function, or production of hemoglobin. These can lead to varying clinical consequences, depending on the nature of the hemoglobin defect.

    Dietary Iron: Adequate dietary iron is essential for the synthesis of hemoglobin in cats. Iron deficiency can lead to anemia, as iron is a critical component of the heme group in hemoglobin molecules.

    In summary, hemoglobin is a vital component of feline physiology, enabling the transport of oxygen and carbon dioxide, which is essential for cellular metabolism and respiratory function. Monitoring hemoglobin levels is a fundamental aspect of veterinary diagnostics and plays an important role in the assessment and management of feline health.



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