Polymyxin B(PMB) antibody/antigen (BSA/OVA/KLH conjugated hapten)

anti-Polymyxin B(PMB) antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-SMT-70-11. BSA-Polymyxin B(PMB)
2. Anti-Polymyxin B(PMB) mouse monoclonal antibody
$2709.00
GMP-SMT-70-21. OVA-Polymyxin B(PMB)
2. Anti-Polymyxin B(PMB) mouse monoclonal antibody
$2709.00
GMP-SMT-70-31. BSA-Polymyxin B(PMB)
2. Anti-Polymyxin B(PMB) human monoclonal antibody
$2709.00
GMP-SMT-70-41. OVA-Polymyxin B(PMB)
2. Anti-Polymyxin B(PMB) human monoclonal antibody
$2709.00
GMP-SMT-70-Ag-1BSA-Polymyxin B(PMB)$756.00
GMP-SMT-70-Ag-2OVA-Polymyxin B(PMB)$756.00
GMP-SMT-70-Ab-1Anti-Polymyxin B(PMB) mouse monoclonal antibody$1953.00
GMP-SMT-70-Ab-2Anti-Polymyxin B(PMB) human monoclonal antibody$1953.00

Size: 1mg | 10mg | 100mg



Product Description


BSA-Polymyxin B(PMB)

Cat No.GMP-SMT-70-Ag-1
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products descriptionCompetitive immunoassay-validated hapten-carrier conjugates BSA-Polymyxin B(PMB) with anti-Hapten antibody. The hapten hapten-carrier conjugates BSA-Polymyxin B(PMB) had been validated with our anti-Hapten antibody Anti-Polymyxin B(PMB) mouse monoclonal antibody via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


OVA-Polymyxin B(PMB)

Cat No.GMP-SMT-70-Ag-2
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products descriptionCompetitive immunoassay-validated hapten-carrier conjugates OVA-Polymyxin B(PMB) with anti-Hapten antibody. The hapten hapten-carrier conjugates OVA-Polymyxin B(PMB) had been validated with our anti-Hapten antibody Anti-Polymyxin B(PMB) mouse monoclonal antibody via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Anti-Polymyxin B(PMB) mouse monoclonal antibody

Cat No.GMP-SMT-70-Ab-1
Host of AntibodyMouse IgG
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb)10-20
Products descriptionThe anti-Hapten antibody against hapten Polymyxin B(PMB) had been validated with our hapten hapten-carrier conjugates BSA-Polymyxin B(PMB) via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Anti-Polymyxin B(PMB) human monoclonal antibody

Cat No.GMP-SMT-70-Ab-2
Host of AntibodyHuman IgG1
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb)10-20
Products descriptionThe anti-Hapten antibody against hapten Polymyxin B(PMB) had been validated with our hapten hapten-carrier conjugates BSA-Polymyxin B(PMB) via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Data / case study


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    Biomarker Information


    1.Polymyxin B (PMB): A Comprehensive Scientific Exploration

    Polymyxin B (PMB), a prominent member of the polymyxin class of antibiotics, holds a significant place in veterinary medicine. In this detailed analysis, we delve into the scientific aspects of PMB, its roles in managing veterinary drug residues and additives, and the paramount importance of precisely measuring its levels.

    Role in Veterinary Drug Residues and Additives (Serial Number 1)

    PMB is a potent antimicrobial agent, primarily employed in veterinary medicine to combat bacterial infections in animals. Its significance in veterinary drug residues and additives is multifaceted:

    2.Residues: When administered to animals, especially in livestock, PMB serves as a critical line of defense against bacterial infections. However, upon slaughter for meat production, ensuring that PMB residues do not exceed permissible limits is essential. This stringent control is necessary to guarantee the safety of meat products destined for human consumption. Regulatory standards, enforced to prevent excessive residues, become the cornerstone in safeguarding public health and maintaining compliance within the industry.

    3.Additives: In certain scenarios, PMB is incorporated as an additive in animal feed or water to foster growth and counteract bacterial infections in livestock. Here, the accurate quantification of PMB levels in these additives is of paramount importance. It ensures the effectiveness and safety of these products, contributing to the overall well-being of the animals and the success of farming operations.

    Importance of Measuring Polymyxin B (PMB) (Serial Number 2)

    The precise measurement of PMB levels in veterinary applications is crucial for a multitude of reasons, underscoring its profound impact on animal health, food safety, and pharmaceutical development:

    4.Safety and Compliance: The administration of PMB to animals demands strict adherence to regulatory standards and guidelines. This is vital to ascertain the safety of meat products that are derived from animals treated with PMB. Rigorous monitoring and accurate measurement are imperative to ensure that PMB residues do not exceed established limits. This stringent control mechanism not only guarantees consumer safety but also fosters trust within the veterinary and food industries.

    5.Efficacy: Precise measurement of PMB levels in animals is not only about ensuring safety but also about confirming its effectiveness in treating bacterial infections. Accurate dosing and continuous monitoring are essential to optimize the therapeutic outcomes. Veterinarians and animal health professionals rely on these measurements to make informed decisions regarding dosage adjustments and treatment protocols.

    6.Antibiotic Resistance: The issue of antibiotic resistance is of global concern. Overuse or inappropriate use of antibiotics, including PMB, can contribute to the development of antibiotic resistance in both animals and humans. Regular measurement of PMB is an essential component of prudent antibiotic stewardship. It helps control the use of this antibiotic, minimizing the risk of resistance and preserving its efficacy for future generations.

    7.Quality Control in Animal Feed: In cases where PMB is utilized as an additive in animal feed or water, its measurement is pivotal for maintaining consistent product quality. Accurate quantification ensures that animals receive the appropriate dosage of PMB, which directly affects their growth, health, and overall well-being. Furthermore, quality control measures in the manufacturing of animal feed additives depend on precise measurements to meet stringent industry standards.

    8.Research and Development: For biopharmaceutical companies, understanding and measuring PMB levels is not just a regulatory necessity but a critical aspect of research and development. PMB serves as a foundational element in the development of various products, including antibodies and competitive antigens. Precise measurements are integral to ensuring the quality and efficacy of these products, which, in turn, contributes to advancements in veterinary medicine and biopharmaceutical science.

    In conclusion, Polymyxin B (PMB) plays a multifaceted role in veterinary medicine, necessitating precise measurement for safety, efficacy, and quality control. Understanding its scientific underpinnings is essential for pharmaceutical companies, veterinary professionals, and the entire food industry. The responsible use and accurate measurement of PMB not only ensure the health and safety of animals but also contribute to the protection of public health and the sustainability of antibiotic efficacy.



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