Ehrlichia Major Antigenic Protein 2 antibody and antigen (recombinant protein)

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Diagnostic anti-Ehrlichia Major Antigenic Protein 2 antibodies pairs and antigen for animal health (animal Cat/Feline, Dog/Canine infectious disease Canine monocytic ehrlichiosis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P017-Tg001-Ag01	Recombinant Ehrlichia Major Antigenic Protein 2 protein	$3090.00
GMP-VT-P017-Tg001-Ab01	Anti-Ehrlichia Major Antigenic Protein 2 mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P017-Tg001-Ab02	Anti-Ehrlichia Major Antigenic Protein 2 mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P017-Tg001-Ab03	Anti-Ehrlichia Major Antigenic Protein 2 human monoclonal antibody (mAb)	$3090.00
GMP-VT-P017-Tg001-Ab04	Anti-Ehrlichia Major Antigenic Protein 2 human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P017-Tg001-Ag01
Product Name	Recombinant Ehrlichia Major Antigenic Protein 2 protein
Pathogen	Ehrlichia
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Ehrlichia Major Antigenic Protein 2 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Ehrlichia level test of animal Cat/Feline, Dog/Canine infectious disease with Canine monocytic ehrlichiosis.
Tag	His
Product description	Recombinant Ehrlichia Major Antigenic Protein 2 proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P017-Tg001-Ab01,GMP-VT-P017-Tg001-Ab02
Pathogen	Ehrlichia
Product Name	Anti-Ehrlichia Major Antigenic Protein 2 mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Ehrlichia Major Antigenic Protein 2 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Ehrlichia antibodies in Ehrlichia level test of animal Cat/Feline, Dog/Canine infectious disease with Canine monocytic ehrlichiosis.
Product description	Anti-Ehrlichia Major Antigenic Protein 2 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Ehrlichia antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P017-Tg001-Ab03,GMP-VT-P017-Tg001-Ab04
Pathogen	Ehrlichia
Product Name	Anti-Ehrlichia Major Antigenic Protein 2 human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Ehrlichia Major Antigenic Protein 2 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Ehrlichia antibodies in Ehrlichia level test of animal Cat/Feline, Dog/Canine infectious disease with Canine monocytic ehrlichiosis.
Product description	Anti-Ehrlichia Major Antigenic Protein 2 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Pathogen Information

Ehrlichia is a type of bacteria that belongs to the family Anaplasmataceae within the order Rickettsiales. This group of bacteria includes other important pathogens such as Anaplasma, Rickettsia, and Orientia. Ehrlichia is a Gram-negative, obligate intracellular bacterium that requires a host cell for survival and replication. The bacterium was first discovered in 1935 by Paul Ehrlich, a German scientist who also developed the concept of chemotherapy.

The main hosts infected by Ehrlichia are humans, dogs, and deer. The diseases caused by Ehrlichia infection include human monocytic ehrlichiosis (HME), human granulocytic anaplasmosis (HGA), canine ehrlichiosis, and deer ehrlichiosis. These diseases can cause severe symptoms such as fever, headache, muscle aches, and fatigue, and can even be fatal if left untreated.

In humans, Ehrlichia infection typically presents as a flu-like illness with fever, chills, headache, and muscle aches. HME is the most common form of Ehrlichia infection in the United States, while HGA is more prevalent in the northeastern and upper Midwestern regions of the country. In dogs, Ehrlichia infection can cause a range of symptoms such as fever, anemia, lethargy, and swollen lymph nodes. In deer, Ehrlichia infection can cause similar symptoms as in dogs.

The diagnosis of Ehrlichia infection is based on clinical signs and symptoms as well as laboratory tests. Laboratory tests for Ehrlichia include PCR-based tests, serological tests, and immunofluorescence assays (IFA). These methods target specific genes or proteins such as the gltA gene, the OMP-1 protein, and the 44-kDa antigen. PCR-based tests are highly sensitive and specific for Ehrlichia detection and can detect the bacterium in blood samples even before the onset of symptoms. Serological tests measure the immune response to Ehrlichia infection and can be used to confirm a diagnosis. IFA is a technique used to detect antibodies to Ehrlichia in patient serum.

Treatment for Ehrlichia infection typically involves the use of antibiotics such as doxycycline or rifampin. Early treatment is important to prevent complications and long-term health effects. In severe cases, hospitalization may be required for supportive care, including intravenous fluids and medications to control fever and pain.

In conclusion, Ehrlichia is a type of Gram-negative, obligate intracellular bacterium that can cause a range of diseases in humans, dogs, and deer. The diagnosis of Ehrlichia infection is based on laboratory tests, including PCR-based tests, serological tests, and immunofluorescence assays. Treatment typically involves the use of antibiotics such as doxycycline or rifampin. Early treatment is crucial to prevent complications and long-term health effects.

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