Feline Immunodeficiency Virus p24 antibody and antigen (recombinant protein)

Diagnostic anti-Feline Immunodeficiency Virus p24 antibodies pairs and antigen for animal health (animal Cat/Feline infectious disease cat HIV or cat AIDS) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No. Description US $ Price (per mg)
GMP-VT-P022-Tg001-Ag01 Recombinant Feline Immunodeficiency Virus p24 protein $3090.00
GMP-VT-P022-Tg001-Ab01 Anti-Feline Immunodeficiency Virus p24 mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P022-Tg001-Ab02 Anti-Feline Immunodeficiency Virus p24 mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P022-Tg001-Ab03 Anti-Feline Immunodeficiency Virus p24 human monoclonal antibody (mAb) $3090.00
GMP-VT-P022-Tg001-Ab04 Anti-Feline Immunodeficiency Virus p24 human monoclonal antibody (mAb) $3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-VT-P022-Tg001-Ag01
Product Name Recombinant Feline Immunodeficiency Virus p24 protein
Pathogen Feline Immunodeficiency Virus
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Feline Immunodeficiency Virus p24 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Feline Immunodeficiency Virus level test of animal Cat/Feline infectious disease with cat HIV or cat AIDS.
Tag His
Product description Recombinant Feline Immunodeficiency Virus p24 proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P022-Tg001-Ab01,GMP-VT-P022-Tg001-Ab02
Pathogen Feline Immunodeficiency Virus
Product Name Anti-Feline Immunodeficiency Virus p24 mouse monoclonal antibody (mAb)
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Recombinant Feline Immunodeficiency Virus p24 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline Immunodeficiency Virus antibodies in Feline Immunodeficiency Virus level test of animal Cat/Feline infectious disease with cat HIV or cat AIDS.
Product description Anti-Feline Immunodeficiency Virus p24 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline Immunodeficiency Virus antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P022-Tg001-Ab03,GMP-VT-P022-Tg001-Ab04
Pathogen Feline Immunodeficiency Virus
Product Name Anti-Feline Immunodeficiency Virus p24 human monoclonal antibody (mAb)
Expression platform CHO
Isotypes Human lgG1
Bioactivity validation Recombinant Feline Immunodeficiency Virus p24 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline Immunodeficiency Virus antibodies in Feline Immunodeficiency Virus level test of animal Cat/Feline infectious disease with cat HIV or cat AIDS.
Product description Anti-Feline Immunodeficiency Virus p24 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


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    Pathogen Information


    Feline Immunodeficiency Virus (FIV), also known as Feline AIDS, is a retrovirus that falls under the family Retroviridae and the genus Lentivirus. This viral pathogen primarily affects domestic cats and various wild feline species, including lions and cougars. FIV infection weakens the immune system of infected individuals, leading to immunodeficiency and making them susceptible to a range of opportunistic infections.

    The structure of FIV is characterized by a spherical shape, encompassing an outer envelope derived from the host cell membrane. Within this envelope lies the viral core, containing essential components of the virus, such as the RNA genome, reverse transcriptase, integrase, protease enzymes, and the p24 capsid protein. The viral genome of FIV is composed of single-stranded RNA, which serves as the genetic material for the virus.

    Transmission of FIV occurs primarily through bites and scratches inflicted during aggressive fights between infected and uninfected cats. The virus can also be transmitted from an infected mother cat to her offspring during pregnancy, birth, or through breastfeeding. However, FIV is not highly contagious, and it does not spread easily through casual contact among cats.

    Once a cat becomes infected with FIV, the virus primarily targets immune cells, particularly T-lymphocytes and macrophages. FIV enters these cells and utilizes its reverse transcriptase enzyme to convert its RNA genome into DNA, which is then integrated into the host cell's DNA. This integration allows the virus to persist within the infected cells, evading the immune system and establishing a chronic infection.

    FIV infection progresses in stages, starting with an initial acute phase that is often asymptomatic or exhibits mild symptoms. During this phase, the virus replicates rapidly, leading to a temporary decrease in the number of circulating CD4+ T cells, which are crucial for immune function. As the infection progresses, the immune system mounts a response, resulting in the production of antibodies against FIV.

    However, despite the immune response, FIV manages to persist in the body and establish a chronic infection. Over time, the virus gradually weakens the immune system, leading to immunodeficiency. This weakened state makes the affected cats highly susceptible to various opportunistic infections and diseases.

    The clinical manifestations of FIV infection can vary widely among infected cats. Some individuals may remain asymptomatic for extended periods, while others may develop a range of symptoms. These symptoms include chronic respiratory infections, recurrent oral and dental problems (such as stomatitis and gingivitis), persistent diarrhea, weight loss, fever, lethargy, neurological disorders, and an increased risk of developing certain types of cancer, most notably lymphoma.

    To diagnose FIV infection, several diagnostic methods are available. One common approach is the use of Enzyme-Linked Immunosorbent Assay (ELISA) tests, which detect the presence of antibodies against the virus in blood or saliva samples. ELISA tests are highly sensitive and specific, allowing for reliable detection of FIV infection. Polymerase Chain Reaction (PCR) tests are another diagnostic tool used to identify the viral RNA in blood or tissue samples. By targeting specific regions of the viral genome such as gag and env genes or the long terminal repeat (LTR) region, PCR tests can provide direct evidence of viral presence even in cases where antibody levels may be low or undetectable. Additionally, Western blotting techniques can be employed to detect antibodies against specific viral proteins, providing confirmatory evidence of FIV infection.

    In conclusion, Feline Immunodeficiency Virus (FIV) is a retrovirus that infects domestic cats and certain wild feline species, causing immunodeficiency and making them vulnerable to various opportunistic infections and diseases. Understanding the structure, transmission, progression, and diagnostic methods related to FIV is crucial for effective management and prevention of the disease in feline populations.



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