Tritrichomoas foetus antibody and antigen (recombinant protein)

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Diagnostic anti-Tritrichomoas foetus antibodies pairs and antigen for animal health (animal Bovines/Cattle, Ovines/Sheep, Caprine/Goat infectious disease Trichomoniasis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P055-Tg001-Ag01	Recombinant Tritrichomoas foetus protein	$3090.00
GMP-VT-P055-Tg001-Ab01	Anti-Tritrichomoas foetus mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P055-Tg001-Ab02	Anti-Tritrichomoas foetus mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P055-Tg001-Ab03	Anti-Tritrichomoas foetus human monoclonal antibody (mAb)	$3090.00
GMP-VT-P055-Tg001-Ab04	Anti-Tritrichomoas foetus human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P055-Tg001-Ag01
Product Name	Recombinant Tritrichomoas foetus protein
Pathogen	Tritrichomoas foetus
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Tritrichomoas foetus antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Tritrichomoas foetus level test of animal Bovines/Cattle, Ovines/Sheep, Caprine/Goat infectious disease with Trichomoniasis.
Tag	His
Product description	Recombinant Tritrichomoas foetus proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P055-Tg001-Ab01,GMP-VT-P055-Tg001-Ab02
Pathogen	Tritrichomoas foetus
Product Name	Anti-Tritrichomoas foetus mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Tritrichomoas foetus antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Tritrichomoas foetus antibodies in Tritrichomoas foetus level test of animal Bovines/Cattle, Ovines/Sheep, Caprine/Goat infectious disease with Trichomoniasis.
Product description	Anti-Tritrichomoas foetus mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Tritrichomoas foetus antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P055-Tg001-Ab03,GMP-VT-P055-Tg001-Ab04
Pathogen	Tritrichomoas foetus
Product Name	Anti-Tritrichomoas foetus human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Tritrichomoas foetus antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Tritrichomoas foetus antibodies in Tritrichomoas foetus level test of animal Bovines/Cattle, Ovines/Sheep, Caprine/Goat infectious disease with Trichomoniasis.
Product description	Anti-Tritrichomoas foetus mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Pathogen Information

Tritrichomonas foetus is a pathogenic protozoan parasite that primarily affects the reproductive and gastrointestinal tracts of various animals. It is most notably known for its impact on cattle, causing a condition called bovine trichomoniasis. In this expanded description, we will delve into the characteristics, host range, disease manifestations, transmission, and diagnostic methods associated with Tritrichomonas foetus.

Tritrichomonas foetus belongs to the phylum Parabasalia and the class Trichomonadea. As a eukaryotic organism, it possesses a nucleus enclosed within a membrane, distinguishing it from prokaryotes such as bacteria. This pear-shaped parasite has a single cell and multiple flagella, which enable its motility and movement through the reproductive and gastrointestinal tracts of its hosts.

The pathogen's reproductive cycle begins when Tritrichomonas foetus colonizes the genital tracts of infected animals. In cows, bulls, and other susceptible hosts, the presence of this parasite can lead to significant reproductive issues. Bovine trichomoniasis is characterized by infertility, early embryonic death, and abortion. Infected bulls act as carriers and can transmit the pathogen to healthy cows during mating, perpetuating the cycle of infection within herds.

Apart from cattle, Tritrichomonas foetus has been found to infect other animal species, including cats, pigs, and humans, albeit with varying levels of clinical significance. In cats, it is associated with chronic diarrhea and persistent colitis. In pigs, Tritrichomonas foetus has been detected in the gastrointestinal tract, but its pathogenic potential and clinical impact are not yet fully understood. While human infection is rare, cases have been reported, primarily linked to sexual contact or ingestion of contaminated food or water.

Transmission of Tritrichomonas foetus occurs primarily through direct contact with infected individuals or through contaminated materials, such as bedding or equipment. In the case of bovine trichomoniasis, sexual transmission during mating is the primary mode of infection. Infected bulls can harbor the pathogen in their preputial cavity and transfer it to susceptible cows during breeding.

Accurate and timely diagnosis of Tritrichomonas foetus infections is crucial for disease control and management. Various diagnostic methods are available, including microscopic examination and nucleic acid-based techniques. Microscopic examination involves the identification of Tritrichomonas foetus in clinical samples, such as vaginal smears or preputial washes, by observing its characteristic morphology under a microscope. However, this method may have limitations in terms of sensitivity and specificity.

Nucleic acid-based techniques, particularly Polymerase Chain Reaction (PCR), have become increasingly popular for detecting Tritrichomonas foetus due to their high sensitivity and specificity. PCR targets specific genes or regions of the parasite's genome, such as the Internal Transcribed Spacer 1 (ITS1) region and adhesin genes, allowing for the rapid and accurate detection of the pathogen in clinical samples. Additionally, Real-Time PCR assays have been developed to provide quantitative information about the infection load, which can be valuable for monitoring disease progression and treatment efficacy.

In conclusion, Tritrichomonas foetus is a significant pathogenic protozoan parasite that affects the reproductive and gastrointestinal tracts of various animals, with bovine trichomoniasis being the most well-known manifestation. Its pear-shaped body, multiple flagella, and colonization in the genital tracts contribute to its ability to cause reproductive issues and infertility. Diagnosis relies on techniques such as microscopic examination and nucleic acid-based methods like PCR, allowing for accurate and timely detection of the parasite. Understanding the characteristics, host range, transmission, and diagnostic methods associated with Tritrichomonas foetus is essential for effective disease control and prevention in affected animal populations.

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