Seneca Valley virus, SVV VP1 antibody and antigen (recombinant protein)

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Diagnostic anti-Seneca Valley virus, SVV VP1 antibodies pairs and antigen for animal health (animal Swine/Porcine/Pig infectious disease idiopathic vesicular disease) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P095-Tg002-Ag01	Recombinant Seneca Valley virus, SVV VP1 protein	$3090.00
GMP-VT-P095-Tg002-Ab01	Anti-Seneca Valley virus, SVV VP1 mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P095-Tg002-Ab02	Anti-Seneca Valley virus, SVV VP1 mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P095-Tg002-Ab03	Anti-Seneca Valley virus, SVV VP1 human monoclonal antibody (mAb)	$3090.00
GMP-VT-P095-Tg002-Ab04	Anti-Seneca Valley virus, SVV VP1 human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P095-Tg002-Ag01
Product Name	Recombinant Seneca Valley virus, SVV VP1 protein
Pathogen	Seneca Valley virus, SVV
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Seneca Valley virus, SVV VP1 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Seneca Valley virus, SVV level test of animal Swine/Porcine/Pig infectious disease with idiopathic vesicular disease.
Tag	His
Product description	Recombinant Seneca Valley virus, SVV VP1 proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P095-Tg002-Ab01,GMP-VT-P095-Tg002-Ab02
Pathogen	Seneca Valley virus, SVV
Product Name	Anti-Seneca Valley virus, SVV VP1 mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Seneca Valley virus, SVV VP1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Seneca Valley virus, SVV antibodies in Seneca Valley virus, SVV level test of animal Swine/Porcine/Pig infectious disease with idiopathic vesicular disease.
Product description	Anti-Seneca Valley virus, SVV VP1 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Seneca Valley virus, SVV antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P095-Tg002-Ab03,GMP-VT-P095-Tg002-Ab04
Pathogen	Seneca Valley virus, SVV
Product Name	Anti-Seneca Valley virus, SVV VP1 human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Seneca Valley virus, SVV VP1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Seneca Valley virus, SVV antibodies in Seneca Valley virus, SVV level test of animal Swine/Porcine/Pig infectious disease with idiopathic vesicular disease.
Product description	Anti-Seneca Valley virus, SVV VP1 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Pathogen Information

Seneca Valley virus (SVV) is a small RNA virus that belongs to the Picornaviridae family. This family comprises numerous small, non-enveloped RNA viruses that can cause a broad range of diseases in both humans and animals. SVV was first identified in 2002 in pigs with vesicular disease and has since been detected in multiple hosts, including cattle and humans.

The genome of SVV consists of a single positive-sense RNA molecule encoding a polyprotein that is cleaved by viral proteases into individual functional proteins. The capsid protein VP1 is the major structural protein of the virus. SVV is able to infect multiple hosts and can cause vesicular disease and fever in swine, as well as aseptic meningitis in humans.

The clinical symptoms of SVV infection are variable and depend on the host species. In pigs, the disease is characterized by vesicular lesions on the skin, particularly the snout, mouth, and feet. In some cases, the disease can progress to systemic infection, which may result in death. In humans, the most common symptom of SVV infection is aseptic meningitis, which is usually self-limiting and resolves within a few days without any specific treatment.

Diagnostic methods for SVV infection include nucleic acid amplification assays, such as Reverse Transcriptase Polymerase Chain Reaction (RT-PCR), real-time RT-PCR, and serological assays such as Enzyme-Linked Immunosorbent Assay (ELISA) and Virus Neutralization Test (VNT). These methods primarily target the genes of the viral RNA genome, specifically the 5'UTR, VP1, and 3Dpol genes.

Prevention and control measures for SVV infection vary depending on the host species. In pigs, good biosecurity practices, such as quarantining new animals, maintaining proper sanitation, and controlling insect vectors, are recommended to prevent SVV transmission. In humans, the best way to prevent infection is to avoid contact with infected animals and practice good hygiene, such as washing hands frequently with soap and water.

In conclusion, Seneca Valley virus (SVV) is a small RNA virus that can cause vesicular disease and fever in swine, as well as aseptic meningitis in humans. The clinical symptoms of SVV infection are variable and depend on the host species. Diagnostic methods for SVV infection primarily target the genes of the viral RNA genome, specifically the 5'UTR, VP1, and 3Dpol genes. Prevention and control measures for SVV infection vary depending on the host species and include good biosecurity practices and practicing good hygiene.

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