Infectious Bronchitis Virus NP antibody and antigen (recombinant protein)

Diagnostic anti-Infectious Bronchitis Virus NP antibodies pairs and antigen for animal health (animal Chicken infectious disease Avian infectious bronchitis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No. Description US $ Price (per mg)
GMP-VT-P169-Tg001-Ag01 Recombinant Infectious Bronchitis Virus NP protein $3090.00
GMP-VT-P169-Tg001-Ab01 Anti-Infectious Bronchitis Virus NP mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P169-Tg001-Ab02 Anti-Infectious Bronchitis Virus NP mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P169-Tg001-Ab03 Anti-Infectious Bronchitis Virus NP human monoclonal antibody (mAb) $3090.00
GMP-VT-P169-Tg001-Ab04 Anti-Infectious Bronchitis Virus NP human monoclonal antibody (mAb) $3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-VT-P169-Tg001-Ag01
Product Name Recombinant Infectious Bronchitis Virus NP protein
Pathogen Infectious Bronchitis Virus
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Infectious Bronchitis Virus NP antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Infectious Bronchitis Virus level test of animal Chicken infectious disease with Avian infectious bronchitis.
Tag His
Product description Recombinant Infectious Bronchitis Virus NP proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P169-Tg001-Ab01,GMP-VT-P169-Tg001-Ab02
Pathogen Infectious Bronchitis Virus
Product Name Anti-Infectious Bronchitis Virus NP mouse monoclonal antibody (mAb)
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Recombinant Infectious Bronchitis Virus NP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Infectious Bronchitis Virus antibodies in Infectious Bronchitis Virus level test of animal Chicken infectious disease with Avian infectious bronchitis.
Product description Anti-Infectious Bronchitis Virus NP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Infectious Bronchitis Virus antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P169-Tg001-Ab03,GMP-VT-P169-Tg001-Ab04
Pathogen Infectious Bronchitis Virus
Product Name Anti-Infectious Bronchitis Virus NP human monoclonal antibody (mAb)
Expression platform CHO
Isotypes Human lgG1
Bioactivity validation Recombinant Infectious Bronchitis Virus NP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Infectious Bronchitis Virus antibodies in Infectious Bronchitis Virus level test of animal Chicken infectious disease with Avian infectious bronchitis.
Product description Anti-Infectious Bronchitis Virus NP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


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    Pathogen Information


    Infectious Bronchitis Virus (IBV): Unveiling the Avian Coronavirus

    Introduction:

    Infectious Bronchitis Virus (IBV), a member of the Coronavirus family, stands as a significant avian pathogen that primarily affects poultry, with chickens being the primary host. It's characterized by its remarkable enveloped, positive-sense, single-stranded RNA genome and is responsible for the occurrence of Infectious Bronchitis (IB), a contagious and economically consequential disease in the poultry industry. In this comprehensive exploration, we delve deeper into the world of IBV, examining its structure, classification, host range, associated diseases, and diagnostic methods.

    Classification and Structure:

    IBV is a virus, specifically classified within the Coronaviridae family. Coronaviruses are a unique group of viruses, characterized by their enveloped structure and a distinctive crown-like appearance when observed under an electron microscope. Unlike prokaryotic or eukaryotic organisms, coronaviruses are a distinct type of virus with their own unique properties.

    The primary genetic component of IBV is the Spike (S) gene, which encodes the spike glycoprotein. This spike glycoprotein plays a pivotal role in the interaction between the virus and host cells. Specifically, it facilitates receptor binding and membrane fusion, enabling the virus to enter host cells, initiate infection, and replicate. The spike glycoprotein is a major target for both the host immune response and diagnostic methods.

    Host Range and Diseases:

    IBV primarily infects chickens, affecting both broilers and layers. While chickens are the most susceptible hosts, other avian species such as turkeys, quails, and pheasants can also be infected, albeit less frequently. The host range is indicative of the adaptability of IBV, making it a concern for avian health across various poultry species.

    The disease primarily associated with IBV is Infectious Bronchitis (IB). IB manifests as respiratory distress, coughing, nasal discharge, and decreased egg production in infected birds. The clinical signs can vary in severity depending on the IBV strain involved. This variation in strains contributes to the complex nature of IB and the challenges it presents to the poultry industry. Vaccination and strict biosecurity measures are often employed to control and prevent IB outbreaks.

    Diagnostic Methods:

    Accurate and timely diagnosis is essential for the management and control of IBV. Various diagnostic methods are utilized to detect the presence of IBV in poultry populations.

    Nucleic Acid-Based Methods: Polymerase Chain Reaction (PCR) and Reverse Transcription PCR (RT-PCR) assays are the cornerstones of IBV diagnosis. These molecular techniques target specific genes or regions of the IBV genome, including the Spike (S) gene, Nucleocapsid (N) gene, and RNA-dependent RNA polymerase (RdRp) gene. The amplification and detection of viral nucleic acids in samples enable the identification of IBV and its specific strains.

    Protein-Based Methods: Enzyme-Linked Immunosorbent Assays (ELISA) are employed for serological diagnosis. ELISA detects IBV-specific antibodies in serum samples, providing crucial information about the presence of antibodies in the bird's immune response. While ELISA is not a direct method of virus detection, it aids in determining exposure to IBV.

    Conclusion:

    Infectious Bronchitis Virus (IBV) remains a substantial concern in the poultry industry, particularly in chickens but also posing a threat to various avian species. Its classification as a coronavirus, the structure of its spike glycoprotein, and the variety of strains highlight the complex nature of this pathogen. Accurate diagnosis through nucleic acid-based and protein-based methods is crucial for controlling and preventing IBV outbreaks, ensuring the health and productivity of poultry populations. Understanding the intricate details of IBV is essential for poultry producers and veterinarians, enabling effective management strategies and safeguarding the poultry industry against this contagious avian disease.



    About GDU


    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.