Salmonella fljB antibody and antigen (recombinant protein)

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Diagnostic anti-Salmonella fljB antibodies pairs and antigen for animal health (animal Avian/Bird/Poultry infectious disease salmonellosis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P221-Tg003-Ag01	Recombinant Salmonella fljB protein	$3090.00
GMP-VT-P221-Tg003-Ab01	Anti-Salmonella fljB mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P221-Tg003-Ab02	Anti-Salmonella fljB mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P221-Tg003-Ab03	Anti-Salmonella fljB human monoclonal antibody (mAb)	$3090.00
GMP-VT-P221-Tg003-Ab04	Anti-Salmonella fljB human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P221-Tg003-Ag01
Product Name	Recombinant Salmonella fljB protein
Pathogen	Salmonella
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Salmonella fljB antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Salmonella level test of animal Avian/Bird/Poultry infectious disease with salmonellosis.
Tag	His
Product description	Recombinant Salmonella fljB proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P221-Tg003-Ab01,GMP-VT-P221-Tg003-Ab02
Pathogen	Salmonella
Product Name	Anti-Salmonella fljB mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Salmonella fljB antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Salmonella antibodies in Salmonella level test of animal Avian/Bird/Poultry infectious disease with salmonellosis.
Product description	Anti-Salmonella fljB mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Salmonella antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P221-Tg003-Ab03,GMP-VT-P221-Tg003-Ab04
Pathogen	Salmonella
Product Name	Anti-Salmonella fljB human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Salmonella fljB antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Salmonella antibodies in Salmonella level test of animal Avian/Bird/Poultry infectious disease with salmonellosis.
Product description	Anti-Salmonella fljB mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Pathogen Information

Salmonella is a pathogenic bacterium that belongs to the genus Salmonella within the family Enterobacteriaceae. This bacterial pathogen is capable of infecting a wide range of hosts, including humans and other animals. In humans, Salmonella can cause a variety of illnesses, including gastroenteritis, septicemia, and typhoid fever.

Salmonella has several key virulence factors that enable it to colonize and cause disease in its host. These include fimbriae, flagella, and outer membrane proteins. Fimbriae are hair-like structures that aid in attachment to host cells and biofilm formation. Flagella are whip-like appendages that allow the bacteria to move through mucus and over surfaces. Outer membrane proteins are another important virulence factor, as they allow the bacteria to acquire nutrients, evade immune responses, and adhere to host cells.

In addition to these virulence factors, Salmonella has a range of other genes and proteins that are important for its survival and pathogenesis. The bacterial chromosome contains the genetic material needed for replication and survival, and a range of plasmids have also been identified that carry genes encoding for antibiotic resistance and other virulence factors. One key protein produced by Salmonella is invasin, which is essential for invasion into host cells.

Salmonella is capable of infecting a wide range of animals, including domestic and wild animals. Transmission can occur through contaminated food and water sources, as well as through direct or indirect contact with infected animals or their feces. In humans, Salmonella infection typically causes gastroenteritis, which is characterized by symptoms such as diarrhea, abdominal pain, and fever. In severe cases, the infection can spread to the bloodstream and other organs, resulting in septicemia.

Another serious illness caused by Salmonella is typhoid fever. This systemic infection is caused by the human-adapted strains of Salmonella enterica serovars Typhi and Paratyphi, which are typically transmitted through contaminated food or water. Symptoms of typhoid fever include fever, abdominal pain, nausea, vomiting, and diarrhea. If left untreated, the infection can progress to septicemia, leading to potentially fatal complications.

Diagnostic methods for Salmonella infections typically involve culture-based methods, which allow for the growth and identification of bacterial colonies. Serological tests can also be used to detect antibodies produced by the host in response to the infection. More recently, nucleic acid-based tests like PCR have become increasingly popular for diagnosing Salmonella infections. These tests target specific genes or proteins associated with Salmonella, such as the invA gene or Salmonella-specific lipopolysaccharide, allowing for rapid and accurate detection of the pathogen. In addition, other diagnostic methods may target specific virulence factors or antibodies produced by the host in response to infection.

In conclusion, Salmonella is a pathogenic bacterium that has the ability to infect a wide range of hosts, including humans and animals. The bacterium possesses several key virulence factors, such as fimbriae, flagella, and outer membrane proteins, that enable it to colonize and cause disease in its host. With appropriate diagnostic techniques, timely treatment and effective public health measures, the impact of Salmonella can be mitigated.

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