Turkey Hemorrhagic Enterititis Virus hexon protein antibody and antigen (recombinant protein)

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Diagnostic anti-Turkey Hemorrhagic Enterititis Virus hexon protein antibodies pairs and antigen for animal health (animal Turkey infectious disease Turkey enteritis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P223-Tg001-Ag01	Recombinant Turkey Hemorrhagic Enterititis Virus hexon protein protein	$3090.00
GMP-VT-P223-Tg001-Ab01	Anti-Turkey Hemorrhagic Enterititis Virus hexon protein mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P223-Tg001-Ab02	Anti-Turkey Hemorrhagic Enterititis Virus hexon protein mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P223-Tg001-Ab03	Anti-Turkey Hemorrhagic Enterititis Virus hexon protein human monoclonal antibody (mAb)	$3090.00
GMP-VT-P223-Tg001-Ab04	Anti-Turkey Hemorrhagic Enterititis Virus hexon protein human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P223-Tg001-Ag01
Product Name	Recombinant Turkey Hemorrhagic Enterititis Virus hexon protein protein
Pathogen	Turkey Hemorrhagic Enterititis Virus
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Turkey Hemorrhagic Enterititis Virus hexon protein antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Turkey Hemorrhagic Enterititis Virus level test of animal Turkey infectious disease with Turkey enteritis.
Tag	His
Product description	Recombinant Turkey Hemorrhagic Enterititis Virus hexon protein proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P223-Tg001-Ab01,GMP-VT-P223-Tg001-Ab02
Pathogen	Turkey Hemorrhagic Enterititis Virus
Product Name	Anti-Turkey Hemorrhagic Enterititis Virus hexon protein mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Turkey Hemorrhagic Enterititis Virus hexon protein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Turkey Hemorrhagic Enterititis Virus antibodies in Turkey Hemorrhagic Enterititis Virus level test of animal Turkey infectious disease with Turkey enteritis.
Product description	Anti-Turkey Hemorrhagic Enterititis Virus hexon protein mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Turkey Hemorrhagic Enterititis Virus antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P223-Tg001-Ab03,GMP-VT-P223-Tg001-Ab04
Pathogen	Turkey Hemorrhagic Enterititis Virus
Product Name	Anti-Turkey Hemorrhagic Enterititis Virus hexon protein human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Turkey Hemorrhagic Enterititis Virus hexon protein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Turkey Hemorrhagic Enterititis Virus antibodies in Turkey Hemorrhagic Enterititis Virus level test of animal Turkey infectious disease with Turkey enteritis.
Product description	Anti-Turkey Hemorrhagic Enterititis Virus hexon protein mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Pathogen Information

THEV belongs to the Adenoviridae family, a group of non-enveloped double-stranded DNA viruses common in humans and other animals. THEV is classified as Avian Adenovirus Group II, which includes several adenovirus serotypes such as 4, 10, 11, and the recently identified serotype 13 (THEV).

THEV has been identified as the causative agent of a widespread infectious disease with high morbidity and mortality rates among turkeys. The disease was first observed in eastern Turkey during the 1970s and has emerged as a significant economic threat to the poultry industry worldwide. The clinical manifestations of THEV infection vary depending on the age and immune status of the host, the virulence of the virus, and environmental factors.

Young turkeys are particularly susceptible to infection and usually develop acute purulent enteritis, characterized by depression, diarrhea, hemorrhagic lesions, and dehydration. Mortality rates among affected birds range from 5-50%, depending on the severity of the disease and the effectiveness of supportive care. In contrast, older turkeys and recovered birds may develop a subclinical or mild form of the disease, with mild to no visible symptoms.

THEV's genome contains approximately 35 kilobase pairs and encodes for several structural and non-structural proteins. The major structural proteins include fiber, hexon, penton base, and protease, which interact to assemble the capsid and mediate viral entry and replication. The fiber protein in particular plays a crucial role in viral binding to host cell receptors and determines the tissue tropism of different adenovirus serotypes.

The diagnosis of THEV infection relies on various techniques, including virus isolation, electron microscopy, serology, and molecular methods such as PCR and qPCR. Virus isolation involves the inoculation of infected tissues onto cell cultures, followed by the detection of cytopathic effect. Transmission electron microscopy enables the visualization of viral particles in infected tissues, whereas serology employs the detection of antibodies against THEV.

Molecular methods such as PCR and qPCR have demonstrated higher sensitivity and specificity for detecting THEV, especially during the early stages of infection. These techniques target specific regions of the THEV genome, such as the hexon gene or fiber protein, and can detect low viral loads with high accuracy. Additionally, ELISA can be used to quantify the presence of antigens or antibodies in infected samples.

In conclusion, Turkey Hemorrhagic Enteritis Virus (THEV) is a significant pathogen that poses a substantial threat to the poultry industry worldwide. The disease caused by THEV is characterized by acute enteritis and hemorrhagic lesions, especially in young turkeys. THEV's genome encodes for several key structural and non-structural proteins, including fiber, hexon, penton base, and protease, which are instrumental in the virus's entry and replication. Diagnostic methods for detecting THEV involve various techniques, including virus isolation, electron microscopy, serology, and molecular methods such as PCR and qPCR.

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