Tritrichomonas galliniae adhesion protein antibody and antigen (recombinant protein)

Diagnostic anti-Tritrichomonas galliniae adhesion protein antibodies pairs and antigen for animal health (animal Bovines/Cattle, Avian/Bird/Poultry infectious disease trichomonosis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No. Description US $ Price (per mg)
GMP-VT-P265-Tg001-Ag01 Recombinant Tritrichomonas galliniae adhesion protein protein $3090.00
GMP-VT-P265-Tg001-Ab01 Anti-Tritrichomonas galliniae adhesion protein mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P265-Tg001-Ab02 Anti-Tritrichomonas galliniae adhesion protein mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P265-Tg001-Ab03 Anti-Tritrichomonas galliniae adhesion protein human monoclonal antibody (mAb) $3090.00
GMP-VT-P265-Tg001-Ab04 Anti-Tritrichomonas galliniae adhesion protein human monoclonal antibody (mAb) $3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-VT-P265-Tg001-Ag01
Product Name Recombinant Tritrichomonas galliniae adhesion protein protein
Pathogen Tritrichomonas galliniae
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Tritrichomonas galliniae adhesion protein antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Tritrichomonas galliniae level test of animal Bovines/Cattle, Avian/Bird/Poultry infectious disease with trichomonosis.
Tag His
Product description Recombinant Tritrichomonas galliniae adhesion protein proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P265-Tg001-Ab01,GMP-VT-P265-Tg001-Ab02
Pathogen Tritrichomonas galliniae
Product Name Anti-Tritrichomonas galliniae adhesion protein mouse monoclonal antibody (mAb)
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Recombinant Tritrichomonas galliniae adhesion protein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Tritrichomonas galliniae antibodies in Tritrichomonas galliniae level test of animal Bovines/Cattle, Avian/Bird/Poultry infectious disease with trichomonosis.
Product description Anti-Tritrichomonas galliniae adhesion protein mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Tritrichomonas galliniae antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P265-Tg001-Ab03,GMP-VT-P265-Tg001-Ab04
Pathogen Tritrichomonas galliniae
Product Name Anti-Tritrichomonas galliniae adhesion protein human monoclonal antibody (mAb)
Expression platform CHO
Isotypes Human lgG1
Bioactivity validation Recombinant Tritrichomonas galliniae adhesion protein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Tritrichomonas galliniae antibodies in Tritrichomonas galliniae level test of animal Bovines/Cattle, Avian/Bird/Poultry infectious disease with trichomonosis.
Product description Anti-Tritrichomonas galliniae adhesion protein mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


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    Pathogen Information


    Tritrichomonas galliniae: Unveiling the Avian Trichomonad

    Introduction:

    Tritrichomonas galliniae, also known as Avian Trichomonad, is a parasitic protozoan that belongs to the family Trichomonadidae. This eukaryotic microorganism is primarily recognized for its pathogenicity in avian species, most notably domestic and wild pigeons and doves. In this comprehensive overview, we will delve into the various facets of Tritrichomonas galliniae, including its classification, structure, host range, associated diseases, and diagnostic methods.

    Pathogen Classification:

    Tritrichomonas galliniae is classified as a eukaryotic protozoan. The term "eukaryotic" underscores its possession of a true nucleus and other membrane-bound organelles, distinguishing it from prokaryotic organisms such as bacteria. Within the realm of protozoans, T. galliniae finds its place in the class Trichomonadida. This class is characterized by the presence of flagella, thread-like structures that facilitate the organism's motility. The flagellated nature of T. galliniae is a defining feature of this pathogen.

    Pathogen Structure:

    The structural simplicity of Tritrichomonas galliniae is a key attribute. This unicellular organism is composed of a nucleus, where genetic material is housed, and a flagellum, a whip-like appendage responsible for its locomotion. The flagellum propels the parasite through the host's tissues, aiding in its survival and proliferation. While specific genes and proteins within T. galliniae are integral to its metabolic processes, motility, and host interactions, the precise identity of these molecules can vary based on research focus and diagnostic methodologies employed.

    Hosts and Diseases:

    Tritrichomonas galliniae has a predilection for avian hosts, with pigeons, doves, and various other bird species falling within its spectrum of infectivity. Avian trichomoniasis, commonly referred to as canker disease, is the principal ailment linked to T. galliniae infection. This disease manifests through the development of lesions in the oral cavity, esophagus, and upper digestive tract of infected birds. These lesions lead to clinical signs that include difficulties in eating, regurgitation, and, in severe cases, mortality. The debilitating impact of avian trichomoniasis has made the study of T. galliniae a significant area of interest in avian pathology and wildlife conservation.

    Diagnostic Methods:

    Accurate diagnosis of Tritrichomonas galliniae infection is critical for the management of avian trichomoniasis. Several diagnostic methods are available for detecting the presence of this protozoan parasite:

    1. Microscopy:

    Microscopic examination is one of the oldest and most direct methods for detecting T. galliniae. Wet mounts or stained smears of avian tissues or fecal samples are scrutinized under a microscope. The characteristic morphology of T. galliniae, including its flagellated form, can be visualized. However, this method may require expertise and may have limitations in terms of sensitivity.

    2. Culture:

    Culturing T. galliniae in specialized media is a confirmatory method. This technique allows researchers and diagnosticians to propagate and isolate the parasite for further analysis. While it can be valuable, it may take time and may not be as readily accessible as molecular methods.

    3. Nucleic Acid-Based Tests:

    Molecular techniques have revolutionized the diagnosis of Tritrichomonas galliniae. Polymerase Chain Reaction (PCR) is the cornerstone of these methods. PCR allows for the amplification and detection of specific DNA sequences from the parasite, enhancing both sensitivity and specificity. The internal transcribed spacer (ITS) region of ribosomal RNA genes is often targeted in PCR-based assays, providing a highly reliable means of identifying T. galliniae DNA.

    4. Protein Detection:

    While nucleic acid-based tests dominate the landscape of Tritrichomonas galliniae diagnostics, certain proteins associated with the parasite may also be utilized in some assays. However, the focus typically centers on nucleic acid detection methods due to their higher accuracy, efficiency, and ease of standardization.

    Conclusion:

    Tritrichomonas galliniae, the avian trichomonad, poses a significant threat to avian species, particularly pigeons and doves. The intricate understanding of its classification, structure, host range, and associated diseases is pivotal for effective disease management. The availability of diverse diagnostic methods, especially nucleic acid-based tests, has enabled precise identification of T. galliniae, facilitating timely interventions to mitigate the impact of avian trichomoniasis on bird populations. As research continues to evolve in the field of avian pathology, the study of Tritrichomonas galliniae remains indispensable in the conservation and protection of avian wildlife.



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