Pre-made Abituzumab benchmark antibody ( Whole mAb, anti-ITGAV therapeutic antibody, Anti-CD51/MSK8/VNRA/VTNR Antibody) for drug discovery and mechanism of action (MOA) research

Cat No.: GMP-Bios-ab-003

Pre-Made Abituzumab biosimilar, Whole mAb, Anti-ITGAV Antibody: Anti-CD51/MSK8/VNRA/VTNR therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Abituzumab is a humanized IgG2 monoclonal antibody (mAb) targeted at CD51 (an integrin) currently in development by Merck KGaA Darmstadt, Germany in an attempt to prevent bone lesion metastases in castration-resistant prostate cancer.

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Catalog No. Package List Price(In USD) Discount off Discount Price
GMP-Bios-ab-003-1mg 1mg 3090 30% 2163

Size: 1mg | 10mg | 100mg



Description

Products Name (INN Index) Pre-Made Abituzumab biosimilar, Whole mAb, Anti-ITGAV Antibody: Anti-CD51/MSK8/VNRA/VTNR therapeutic antibody
INN Name Abituzumab
TargetITGAV
FormatWhole mAb
DerivationHumanized
Species ReactivityHuman
CH1 IsotypeIgG2
VD LCKappa
Highest_Clin_Trial (Jan '20)Phase-II
Est. StatusActive
100% SI StructureNone
99% SI StructureNone
95-98% SI StructureNone
Year Proposed2013
Year Recommended2014
CompaniesMerck
Conditions Approvedna
Conditions ActiveColorectal cancer;Systemic scleroderma
Conditions DiscontinuedOvarian cancer;Prostate cancer;Solid tumours
Development Techna