Pre-made Muromonab benchmark antibody ( Whole mAb, anti-CD3E therapeutic antibody, Anti-T3E/TCRE/IMD18/CD3epsilon Antibody) for drug discovery and mechanism of action (MOA) research

Cat No.: GMP-Bios-ab-360

Pre-Made Muromonab biosimilar, Whole mAb, Anti-CD3E Antibody: Anti-T3E/TCRE/IMD18/CD3epsilon therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Muromonab-CD3 (trade name Orthoclone OKT3, marketed by Janssen-Cilag) is an immunosuppressant drug given to reduce acute rejection in patients with organ transplants. It is a monoclonal antibody targeted at the CD3 receptor, a membrane protein on the surface of T cells. It was the first monoclonal antibody to be approved for clinical use in humans.

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Catalog No. Package List Price(In USD) Discount off Discount Price
GMP-Bios-ab-360-1mg 1mg 3090 30% 2163

Size: 1mg | 10mg | 100mg



Description

Products Name (INN Index) Pre-Made Muromonab biosimilar, Whole mAb, Anti-CD3E Antibody: Anti-T3E/TCRE/IMD18/CD3epsilon therapeutic antibody
INN Name Muromonab
TargetCD3E
FormatWhole mAb
Derivation
Species ReactivityHuman
CH1 IsotypeIgG2a
VD LCKappa
Highest_Clin_Trial (Jan '20)Approved
Est. StatusDiscontinued
100% SI Structure1sy6:HL
99% SI StructureNone
95-98% SI StructureNone
Year Proposed1988
Year Recommended1989
CompaniesCancer Research UK;Ortho-McNeil;XOMA
Conditions Approvedna
Conditions Activena
Conditions DiscontinuedDiabetes mellitus;Graft-versus-host disease;Renal transplant rejection;Rheumatoid arthritis
Development Techna