D-Dimer Antibodies & Antigens for Veterinary Diagnostics

D-Dimer is a soluble fibrin which reveals coagulation and thrombosis faculties in animals. It shows that Anti-D-Dimer antibodies are applied in veterinary medicine for blood clotting analysis in order to diagnose DIC and deep vein thrombosis, which is of great significance to animal health and preventing severe coagulation diseases.


Product list of GeneMedi's D-Dimer products


Catalog No. Products Name Detected Species Disease/Condition Products Type Products Information
GMP-FEL-D-Dimer-Ag Feline D dimer (D-Dimer) antigen Cat/Feline Thrombosis, disseminated intravascular coagulation (DIC) peptide-(naked/BSA/OVA) Details
GMP-FEL-D-Dimer-Ab Anti-Feline D dimer (D-Dimer) antibody Cat/Feline Thrombosis, disseminated intravascular coagulation (DIC) antibody(Fc/mFc) Details
GMP-CAN-D-Dimer-Ag Canine D dimer (D-Dimer) antigen Dog/Canine Thrombosis, disseminated intravascular coagulation (DIC) peptide-(naked/BSA/OVA) Details
GMP-CAN-D-Dimer-Ab Anti-Canine D dimer (D-Dimer) antibody Dog/Canine Thrombosis, disseminated intravascular coagulation (DIC) antibody(Fc/mFc) Details
GMP-BOV-D-Dimer-Ag Bovine D dimer (D-Dimer) antigen Bovines/Cattle Deep vein thrombosis (DVT) peptide-(naked/BSA/OVA) Details
GMP-BOV-D-Dimer-Ab Anti-Bovine D dimer (D-Dimer) antibody Bovines/Cattle Deep vein thrombosis (DVT) antibody(Fc/mFc) Details
GMP-EQU-D-Dimer-Ag Equine D dimer (D-Dimer) antigen Equine/Horse Thrombosis, disseminated intravascular coagulation (DIC) peptide-(naked/BSA/OVA) Details
GMP-EQU-D-Dimer-Ab Anti-Equine D dimer (D-Dimer) antibody Equine/Horse Thrombosis, disseminated intravascular coagulation (DIC) antibody(Fc/mFc) Details


Understanding D-Dimer: Its Role and Significance in Animals

D-Dimer is the reduced product of blood fibrin that circulates in the blood stream after the clot has been dissolved by fibrinolysis. It is a degradation product of Fibrin, which is a building block of the blood clots generally referred to as a clot. Like for human patients, the degrees of D-Dimer in animals are accrued in an attempt to help determine if there is an active clotting and clot breakdown process actually going on in the body.

Structure of DM1.

D-Dimer

Detecting Thrombotic Disorders: How D-Dimer Helps Identify Veterinary Diseases

In veterinary medicine, elevated D-Dimer levels can indicate various conditions related to abnormal clotting or thrombosis, including:In veterinary medicine, elevated D-Dimer levels can indicate various conditions related to abnormal clotting or thrombosis, including:

· Disseminated Intravascular Coagulation (DIC): A critical illness wherein there is formation of clots in different organs, use up of clotting factors and platelets, therefore causing hemorrhage.

· Deep Vein Thrombosis (DVT): It is a formation of a blood clot in the deep vein, which if travels up to the lungs may be dangerous to the client’s life due to pulmonary embolism.

· Pulmonary Embolism (PE): A clot or plug in one of the pulmonary artery which is in the lungs commonly originated from the legs and other parts of the body.

· Other Thromboembolic Diseases: Situation that develops and causes possibly leads to blockage of circulation in the body, for instance in the heart; causes heart attack or in the brain; causes stroke.

The test for D-Dimer in animals is highly appropriate in the emergency and critical care as early and correct diagnosis of these conditions can be very much of essence. However, it is necessary to state that, although the increase in D-Dimer level indicates the existence of thromboembolic diseases, it does not indicate the location or cause of the thrombi. D-Dimer has been also increased in the conditions that are not necessary associated with clotting disorders but are associated with inflammation, cancer, and some infectious diseases; thus, results need to be considered in conjunction with clinical signs and other diagnostic results.

Such a test has to be used together with other methods because the D-Dimer levels may be affected by other factors indicating that a veterinarian may rely on this test to look at an animal’s overall health and treatment plan.

The Role of D-Dimer in Diagnosing Thrombotic Disorders in Veterinary Medicine
Animals Possible Diseases Listed Specimens/Biofluids Measurement Method
Dog Disseminated Intravascular Coagulation (DIC), Deep Vein Thrombosis (DVT), Pulmonary Embolism (PE), Heartworm Disease, Cancer, Traumatic injuries, Surgery-related thrombosis, Immune-mediated hemolytic anemia (IMHA), Sepsis, Liver disease Blood Immunoassay
Cat Arterial Thromboembolism (ATE), Disseminated Intravascular Coagulation (DIC), Heartworm Disease, Cancer, Traumatic injuries, Surgery-related thrombosis, Pancreatitis, Sepsis, Liver disease, Feline Infectious Peritonitis (FIP) Blood Immunoassay
Horse Disseminated Intravascular Coagulation (DIC), Colic with thrombosis, Laminitis, Post-surgical Thromboembolism, Septicemia, Liver disease, Neonatal isoerythrolysis, Pneumonia leading to PE, Traumatic injuries, Immune-mediated diseases Blood Immunoassay
Cattle Disseminated Intravascular Coagulation (DIC), Thromboembolic pneumonia, Hardware disease with thrombosis, Postparturient Hemorrhagic Syndrome (PPHS), Septicemia, Liver disease, Traumatic injuries, Surgery-related thrombosis, Mastitis with sepsis, Metritis with sepsis Blood Immunoassay




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