Canine D-Dimer antibody and antigen (recombinant protein)

Diagnostic anti-Canine D-Dimer antibodies pairs and antigen for animal health (animal Dog/Canine Thrombosis, disseminated intravascular coagulation (DIC)) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-CAN-D-Dimer-Ag01Canine D-Dimer$3090.00
GMP-CAN-D-Dimer-Ab01Anti-Canine D-Dimer mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-D-Dimer-Ab02Anti-Canine D-Dimer mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-D-Dimer-Ab03Anti-Canine D-Dimer human monoclonal antibody (mAb)$3090.00
GMP-CAN-D-Dimer-Ab04Anti-Canine D-Dimer human monoclonal antibody (mAb)$3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-CAN-D-Dimer-Ag01
Product NameCanine D-Dimer
Target/BiomarkerCanine D-Dimer
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Canine D-Dimer antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in D-Dimer level test of animal Dog/Canine with Thrombosis, disseminated intravascular coagulation (DIC).
TagHis
Reconized/Reactive SpecicsCanine D-Dimer
Product descriptionRecombinant Canine D-Dimer protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-D-Dimer-Ab01,GMP-CAN-D-Dimer-Ab02
Target/BiomarkerCanine D-Dimer
Product NameAnti-Canine D-Dimer mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Canine D-Dimer antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine D-Dimer antibodies in Canine D-Dimer level test of animal Dog/Canine with Thrombosis, disseminated intravascular coagulation (DIC).
Product descriptionAnti-Canine D-Dimer mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine D-Dimer antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-D-Dimer-Ab03,GMP-CAN-D-Dimer-Ab04
Target/BiomarkerCanine D-Dimer
Product NameAnti-Canine D-Dimer human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Canine D-Dimer antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine D-Dimer antibodies in Canine D-Dimer level test of animal Dog/Canine with Thrombosis, disseminated intravascular coagulation (DIC).
Product descriptionAnti-Canine D-Dimer mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    D-Dimer, as a biomarker, holds a significant position in veterinary hematology and clinical diagnostics, particularly when it comes to the canine population. To delve into its intricacies, we must first understand the broader context of coagulation and fibrinolysis within a dog's circulatory system.

    In simple terms, D-Dimer is a small protein fragment that originates during the dissolution of fibrin clots. Fibrin, a critical component in blood clot formation, is a mesh-like protein structure that traps blood cells to stop bleeding when an injury occurs. However, maintaining a delicate balance in the coagulation process is vital. In dogs, as in humans, there are times when this balance can be disrupted, leading to excessive or inadequate blood clot formation.

    D-Dimer enters the picture when these fibrin clots break down, either naturally or due to medical interventions. It acts as a marker for this process, indicating the presence of ongoing or recent coagulation activity. To detect D-Dimer in a dog's blood, veterinarians use specialized laboratory tests. Elevated D-Dimer levels suggest that the balance of clot formation and dissolution may be skewed, necessitating further investigation.



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