Human DNASE1L3/DHP2/DNAS1L3 ORF/cDNA clone-Lentivirus plasmid (NM_004944.4)

Cat. No.: pGMLV001380
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human DNASE1L3/DHP2/DNAS1L3 Lentiviral expression plasmid for DNASE1L3 lentivirus packaging, DNASE1L3 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Product Description

Catalog ID pGMLV001380
Gene Name DNASE1L3
Accession Number NM_004944.4
Gene ID 1776
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 918 bp
Gene Alias DHP2,DNAS1L3,LSD,SLEB16
Fluorescent Reporter Null
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGTCACGGGAGCTGGCCCCACTGCTGCTTCTCCTCCTCTCCATCCACAGCGCCCTGGCCATGAGGATCTGCTCCTTCAACGTCAGGTCCTTTGGGGAAAGCAAGCAGGAAGACAAGAATGCCATGGATGTCATTGTGAAGGTCATCAAACGCTGTGACATCATACTCGTGATGGAAATCAAGGACAGCAACAACAGGATCTGCCCCATACTGATGGAGAAGCTGAACAGAAATTCAAGGAGAGGCATAACGTACAACTATGTGATTAGCTCTCGGCTTGGAAGAAACACATATAAAGAACAATATGCCTTTCTCTACAAGGAAAAGCTGGTGTCTGTGAAGAGGAGTTATCACTACCATGACTATCAGGATGGAGACGCAGATGTGTTTTCCAGGGAGCCCTTTGTGGTCTGGTTCCAATCTCCCCACACTGCTGTCAAAGACTTCGTGATTATCCCCCTGCACACCACCCCAGAGACATCCGTTAAGGAGATCGATGAGTTGGTTGAGGTCTACACGGACGTGAAACACCGCTGGAAGGCGGAGAATTTCATTTTCATGGGTGACTTCAATGCCGGCTGCAGCTACGTCCCCAAGAAGGCCTGGAAGAACATCCGCTTGAGGACTGACCCCAGGTTTGTTTGGCTGATCGGGGACCAAGAGGACACCACGGTGAAGAAGAGCACCAACTGTGCATATGACAGGATTGTGCTTAGAGGACAAGAAATCGTCAGTTCTGTTGTTCCCAAGTCAAACAGTGTTTTTGACTTCCAGAAAGCTTACAAGCTGACTGAAGAGGAGGCCCTGGATGTCAGCGACCACTTTCCAGTTGAATTTAAACTACAGTCTTCAAGGGCCTTCACCAACAGCAAAAAATCTGTCACTCTAAGGAAGAAAACAAAGAGCAAACGCTCCTAG
ORF Protein Sequence MSRELAPLLLLLLSIHSALAMRICSFNVRSFGESKQEDKNAMDVIVKVIKRCDIILVMEIKDSNNRICPILMEKLNRNSRRGITYNYVISSRLGRNTYKEQYAFLYKEKLVSVKRSYHYHDYQDGDADVFSREPFVVWFQSPHTAVKDFVIIPLHTTPETSVKEIDELVEVYTDVKHRWKAENFIFMGDFNAGCSYVPKKAWKNIRLRTDPRFVWLIGDQEDTTVKKSTNCAYDRIVLRGQEIVSSVVPKSNSVFDFQKAYKLTEEEALDVSDHFPVEFKLQSSRAFTNSKKSVTLRKKTKSKRS

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-SE0893-Ab Anti-DNSL3/ DNASE1L3/ DHP2 functional antibody
    Target Antigen GM-Tg-g-SE0893-Ag DNASE1L3 protein
    ORF Viral Vector pGMLP002363 Human DNASE1L3 Lentivirus plasmid
    ORF Viral Vector pGMLV001380 Human DNASE1L3 Lentivirus plasmid
    ORF Viral Vector pGMPC001849 Human DNASE1L3 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP002363 Human DNASE1L3 Lentivirus particle
    ORF Viral Vector vGMLV001380 Human DNASE1L3 Lentivirus particle


    Target information

    Target ID GM-SE0893
    Target Name DNASE1L3
    Gene ID 1776, 13421, 702613, 116687, 101099361, 476576, 512512, 100057863
    Gene Symbol and Synonyms DHP2,DNAS1L3,DNASE1L3,DNasegamma,LSD,SLEB16
    Uniprot Accession Q13609
    Uniprot Entry Name DNSL3_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000163687
    Target Classification Not Available

    This gene encodes a member of the deoxyribonuclease I family. The encoded protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Mutations in this gene are a cause of systemic lupus erythematosus-16. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]



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