Human SOS1/GF1/GGF1 ORF/cDNA clone-Lentivirus particle (NM_005633.3)

Cat. No.: vGMLP005713

Pre-made Human SOS1/GF1/GGF1 Lentiviral expression plasmid for SOS1 lentivirus packaging, SOS1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name lentivirus Grade lentivirus quantity
vGMLP005713 Human SOS1 Lentivirus particle Pilot Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
Research Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMLP005713
Gene Name SOS1
Accession Number NM_005633.3
Gene ID 6654
Species Human
Product Type Lentivirus particle (overexpression)
Insert Length 4002 bp
Gene Alias GF1,GGF1,GINGF,HGF,NS4,SOS-1
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCAGGCGCAGCAGCTGCCCTACGAGTTTTTCAGCGAAGAGAACGCGCCCAAGTGGCGGGGACTACTGGTGCCTGCGCTGAAAAAGGTCCAGGGGCAAGTTCATCCTACTCTCGAGTCTAATGATGATGCTCTTCAGTATGTTGAAGAATTAATTTTGCAATTATTAAATATGCTATGCCAAGCTCAGCCCCGAAGTGCTTCAGATGTAGAGGAACGTGTTCAAAAAAGTTTCCCTCATCCAATTGATAAATGGGCAATAGCTGATGCCCAATCAGCTATTGAAAAGAGGAAGCGAAGAAACCCTTTATCTCTCCCAGTAGAAAAAATTCATCCTTTATTAAAGGAGGTCCTAGGTTATAAAATTGACCACCAGGTTTCTGTTTACATAGTAGCAGTCTTAGAATACATTTCTGCAGACATTTTAAAGCTGGTTGGGAATTATGTAAGAAATATACGGCATTATGAAATTACAAAACAAGATATTAAAGTGGCAATGTGTGCTGACAAGGTATTGATGGATATGTTTCATCAAGATGTAGAAGATATTAATATATTATCTTTAACTGACGAAGAGCCTTCCACCTCAGGAGAACAAACTTACTATGATTTGGTAAAAGCATTTATGGCAGAAATTCGACAATATATAAGGGAACTAAATCTAATTATAAAAGTTTTTAGAGAGCCCTTTGTCTCCAATTCAAAATTGTTTTCAGCTAATGATGTAGAAAATATATTTAGTCGCATAGTAGATATACATGAACTTAGTGTAAAGTTACTGGGCCATATAGAAGATACAGTAGAAATGACAGATGAAGGCAGTCCCCATCCACTAGTAGGAAGCTGCTTTGAAGACTTAGCAGAGGAACTGGCATTTGATCCATATGAATCGTATGCTCGAGATATTTTGCGACCTGGTTTTCATGATCGTTTCCTTAGTCAGTTATCAAAGCCTGGGGCAGCACTTTATTTGCAGTCAATAGGCGAAGGTTTCAAAGAAGCTGTTCAATATGTTTTACCCAGGCTGCTTCTGGCCCCTGTTTACCACTGTCTCCATTACTTTGAACTTTTGAAGCAGTTAGAAGAAAAAAGTGAAGATCAAGAAGACAAGGAATGTTTAAAACAAGCAATAACAGCTTTGCTTAATGTTCAGAGTGGTATGGAAAAAATATGTTCTAAAAGTCTTGCAAAACGAAGACTGAGTGAATCTGCATGTCGGTTTTATAGTCAGCAAATGAAGGGGAAACAACTAGCAATCAAGAAGATGAACGAGATTCAGAAGAATATTGATGGTTGGGAGGGAAAAGACATTGGACAGTGTTGTAATGAATTTATAATGGAAGGAACTCTTACACGTGTAGGAGCCAAACATGAGAGACACATATTTCTCTTTGATGGCTTAATGATTTGCTGTAAATCAAATCATGGGCAGCCAAGACTTCCTGGTGCTAGCAATGCAGAATATCGTCTTAAAGAAAAGTTTTTTATGCGAAAGGTACAAATTAATGATAAAGATGACACCAATGAATACAAGCATGCTTTTGAAATAATTTTAAAAGATGAAAATAGTGTTATATTTTCTGCCAAGTCAGCTGAAGAGAAAAACAATTGGATGGCAGCATTGATATCTTTACAGTACCGGAGTACACTGGAAAGGATGCTTGATGTAACAATGCTACAGGAAGAGAAAGAGGAGCAGATGAGGCTGCCTAGTGCTGATGTTTATAGATTTGCAGAGCCTGACTCTGAAGAGAATATTATATTTGAAGAGAACATGCAGCCCAAGGCTGGAATTCCAATTATCAAAGCAGGAACTGTTATTAAACTTATAGAGAGGCTTACGTACCATATGTACGCAGATCCCAATTTTGTTCGGACATTTCTTACAACATACAGATCCTTTTGCAAACCTCAAGAACTACTGAGTCTTATAATAGAAAGGTTTGAAATTCCAGAGCCTGAGCCAACAGAAGCTGATCGCATAGCTATAGAGAATGGAGATCAACCCTTGAGTGCAGAACTGAAAAGATTTAGAAAAGAATATATACAGCCTGTGCAACTGCGAGTATTAAATGTATGTCGGCACTGGGTAGAGCACCACTTCTATGATTTTGAAAGAGATGCATATCTTTTGCAACGAATGGAAGAATTTATTGGAACAGTAAGAGGTAAAGCAATGAAAAAATGGGTTGAATCCATCACTAAAATAATCCAAAGGAAAAAAATTGCAAGAGACAATGGACCAGGTCATAATATTACATTTCAGAGTTCACCTCCCACAGTTGAGTGGCATATAAGCAGACCTGGGCACATAGAGACTTTTGACCTGCTCACCTTACACCCAATAGAAATTGCTCGACAACTCACTTTACTTGAATCAGATCTATACCGAGCTGTACAGCCATCAGAATTAGTTGGAAGTGTGTGGACAAAAGAAGACAAAGAAATTAACTCTCCTAATCTTCTGAAAATGATTCGACATACCACCAACCTCACTCTGTGGTTTGAGAAATGTATTGTAGAAACTGAAAATTTAGAAGAAAGAGTAGCTGTGGTGAGTCGAATTATTGAGATTCTACAAGTCTTTCAAGAGTTGAACAACTTTAATGGTGTCCTTGAGGTTGTCAGTGCTATGAATTCATCACCTGTTTACAGACTAGACCACACATTTGAGCAAATACCAAGTCGCCAGAAGAAAATTTTAGAAGAAGCTCATGAATTGAGTGAAGATCACTATAAGAAATATTTGGCAAAACTCAGGTCTATTAATCCACCATGTGTGCCTTTCTTTGGAATTTATCTCACTAATATCTTGAAAACAGAAGAAGGCAACCCTGAGGTCCTAAAAAGACATGGAAAAGAGCTTATAAACTTTAGCAAAAGGAGGAAAGTAGCAGAAATAACAGGAGAGATCCAGCAGTACCAAAATCAGCCTTACTGTTTACGAGTAGAATCAGATATCAAAAGGTTCTTTGAAAACTTGAATCCGATGGGAAATAGCATGGAGAAGGAATTTACAGATTATCTTTTCAACAAATCCCTAGAAATAGAACCACGAAACCCTAAGCCTCTCCCAAGATTTCCAAAAAAATATAGCTATCCCCTAAAATCTCCTGGTGTTCGTCCATCAAACCCAAGACCAGGTACCATGAGGCATCCCACACCTCTGCAGCAGGAGCCAAGGAAAATTAGTTATAGTAGGATCCCTGAAAGTGAAACAGAAAGTACAGCATCTGCACCAAATTCTCCAAGAACACCGTTAACACCTCCGCCTGCTTCTGGTGCTTCCAGTACCACAGATGTTTGCAGTGTATTTGATTCCGATCATTCGAGCCCTTTTCACTCAAGCAATGATACCGTCTTTATCCAAGTTACTCTGCCCCATGGCCCAAGATCTGCTTCTGTATCATCTATAAGTTTAACCAAAGGCACTGATGAAGTGCCTGTCCCTCCTCCTGTTCCTCCACGAAGACGACCAGAATCTGCCCCAGCAGAATCTTCACCATCTAAGATTATGTCTAAGCATTTGGACAGTCCCCCAGCCATTCCTCCTAGGCAACCCACATCAAAAGCCTATTCACCACGATATTCAATATCAGACCGGACCTCTATCTCAGACCCTCCTGAAAGCCCTCCCTTATTACCACCACGAGAACCTGTGAGGACACCTGATGTTTTCTCAAGCTCACCACTACATCTCCAACCTCCCCCTTTGGGCAAAAAAAGTGACCATGGCAATGCCTTCTTCCCAAACAGCCCTTCCCCCTTTACACCACCTCCTCCTCAAACACCTTCTCCTCACGGCACAAGAAGGCATCTGCCATCACCACCATTGACACAAGAAGTGGACCTTCATTCCATTGCTGGGCCGCCTGTTCCTCCACGACAAAGCACTTCTCAACATATCCCTAAACTCCCTCCAAAAACTTACAAAAGGGAGCACACACACCCATCCATGCACAGAGATGGACCACCACTGTTGGAGAATGCCCATTCTTCCTGA
ORF Protein Sequence MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLCQAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGYKIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDVEDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSANDVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYARDILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQLEEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPIIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSNDTVFIQVTLPHGPRSASVSSISLTKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISDRTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPPPQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-TA061-Ab Anti-SOS1 monoclonal antibody
    Target Antigen GM-Tg-g-TA061-Ag SOS1 protein
    ORF Viral Vector pGMLP005713 Human SOS1 Lentivirus plasmid
    ORF Viral Vector vGMLP005713 Human SOS1 Lentivirus particle


    Target information

    Target ID GM-TA061
    Target Name SOS1
    Gene ID 6654, 20662, 713777, 313845, 101098862, 483042, 537682, 100053889
    Gene Symbol and Synonyms 4430401P03Rik,9630010N06,GF1,GGF1,GINGF,HGF,NS4,SOS-1,SOS1
    Uniprot Accession Q07889
    Uniprot Entry Name SOS1_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000115904
    Target Classification Tumor-associated antigen (TAA)

    This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008]



    About GMVC

    GDU

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