Products & Information Collection of New variant SARS-COV-2 (2019nCOV) -Brazilian variants: P.1 lineage(B.1.1.28.1)
The world is in midst of the COVID-19 pandemic.The SARS-CoV-2 lineage B.1.1.28 has been evolving in Brazil since February 2020. A new lineage, named P.1 (B.1.1.28.1), contains convergent mutations in the spike (S) protein, including several receptor binding domain (spike RBD) mutations E484K, K417T, and N501Y.
| Spike Mutation in SARS-COV-2 (2019nCOV) Brazilian variant P.1 lineage (B.1.1.28.1) |
Spike-S1 Subunit N Terminal |
L18F | |
| T20N | |||
| P26S | |||
| D138Y | |||
| R190S | |||
| Spike-S1-RBD | K417N | Important residues mutation | |
| E484K | |||
| N501Y | |||
| Spike-S1 Subunit C Terminal | D614G | A popular mutation in different new SARS-CoV-2 lineage | |
| H655Y | |||
| Spike-S2 Subunit | T1027I | ||
| V1176F |
GeneMedi pseudotype virus (pseudovirus) of SARS-COV-2 (2019nCOV) P.1 lineage (B.1.1.28.1, Brazilian variant)
SARS-COV-2 (2019nCOV)-P.1 lineage(B.1.1.28.1, Brazilian variant) of Spike protein & ACE2 competition binding assay for efficacy evaluation of COVID-19 vaccines and therapeutic antibodiess
GeneMedi codon-optimized spike mammalian expression vector for SARS-COV-2 (2019nCOV) - P.1 lineage(B.1.1.28.1, Brazilian variant)
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