Spike H49Y mutation SARS-CoV-2(2019nCoV)
and H49Y Pseudotyped Vrus Basd Neutraliztion Assay

Order informatioin

Delivery impact due to the Coronavirus Outbreak

With the COVID-19 outbreak in the world, many flights have been cancelled. In order for the customer to receive the goods properly, we use the FedEx Customized Freight (FCF) of Fedex which demands a higher fee. If the delivery fee is more expensive in your area, we will contact you by mail.

Description

The outbreak of COVID-19, caused by SARS-CoV-2 (2019-nCoV), has been a global public health threat and caught the worldwide concern. GeneMedi has developed SARS-CoV-2 wildtype and mutation variants pseudovirus production system, from which the SARS-CoV-2 wildtype and mutation variants pseudotyped virus can be handled in biosafety level 2 (BSL-2).

GeneMedi develop COVID-19 related SARS-CoV-2 (2019-nCoV)Pseudotyped virus of SARS-CoV-2 Spike Mutation Variants including D614G,S943P,V367F, G476S, V483A, H49Y, Q239K, A831V, P1263L, D839Y/N/E:D839Y,D839N,D839E and so on.

SARS-CoV-2 Pseudotyped virus with Spike D614G mutation:Increasing frequency and global distribution.
SARS-CoV-2 Pseudotyped virus with Spike S943P mutation:It is found only in Belgium
SARS-CoV-2 Pseudotyped virus with Spike V367F mutation:
SARS-CoV-2 Pseudotyped virus with Spike G476S mutation
SARS-CoV-2 Pseudotyped virus with Spike V483A mutation
SARS-CoV-2 Pseudotyped virus with Spike H49Y mutation
SARS-CoV-2 Pseudotyped virus with Spike Q239K mutation
SARS-CoV-2 Pseudotyped virus with Spike A831V mutation
SARS-CoV-2 Pseudotyped virus with Spike P1263L mutation
SARS-CoV-2 Pseudotyped virus with Spike D839Y/N/E-D839Y mutation
SARS-CoV-2 Pseudotyped virus with Spike D839Y/N/E-D839N mutation
SARS-CoV-2 Pseudotyped virus with Spike D839Y/N/E-D839E mutation
SARS-CoV-2 Pseudotyped virus with P2-mutated Spike protein trimer variant (P2-mutant, S1/S2 cleavage site (furin cleavage sequence)-mutant,trimerization modified) mutation
SARS-CoV-2 Pseudotyped virus with Spike of SARS-COV-2 B.1.1.7 lineage mutation
SARS-CoV-2 Pseudotyped virus with Spike(S1+S2) N501Y mutation mutation
SARS-CoV-2 Pseudotyped virus with Spike(S1+S2)-HV 69-70 Deletion mutation(ΔH69/ΔV70) mutation

GeneMedi’s Pseudovirus Based Neutralization Assay (PBNA) is a conventional assay method that is suitable for High-Throughout Screening (HTS) without live virus engaged. The Pseudovirus Based Neutralization Assay can be used for evaluating:

1) Neutralizing antibodies
2) Peptides blockers (peptide inhibitors)
3) Types of Vaccines3
4) Compounds targeting Spike induced cell-fusion.

GeneMedi offers:

1.SARS-CoV-2 Pseudotyped virus packaging and production
2.Effector cells: human ACE2 overexpression stable HEK293T cell lines
3.SARS-CoV-2(2019nCoV) Pseudotyped Virus Based Neutralization Assay service.