SOLIDEX®-ISOEx Anti-G4S Linker Nanobeads (Column-Based) (Cat No.:GMLS-Tag003-Ab01-nanoIMB)


Paramagnetic 50 nm nanobeads directly conjugated with a highly specific monoclonal antibody targeting the classic (GGGGS)n flexible linker (G4S linker) within the single-chain variable fragment (scFv) of CAR constructs. Designed for the high-purity, column-based magnetic enrichment or depletion of G4S-containing CAR-expressing immune cells.


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Order information


Catalog No. Product Name Size Price(In USD)
SOLIDEX®-ISOEx Anti-G4S Linker Nanobeads (Column-Based) 0.5 mL
SOLIDEX®-ISOEx Anti-G4S Linker Nanobeads (Column-Based) 1 mL

Description


Cat No. GMLS-Tag003-Ab01-nanoIMB
Product Name SOLIDEX®-ISOEx Anti-G4S Linker Nanobeads (Column-Based)
Description

Paramagnetic 50 nm nanobeads directly conjugated with a highly specific monoclonal antibody targeting the classic (GGGGS)n flexible linker (G4S linker) within the single-chain variable fragment (scFv) of CAR constructs. Designed for the high-purity, column-based magnetic enrichment or depletion of G4S-containing CAR-expressing immune cells.
Application

Universal CAR Cell Enrichment: Direct, antigen-independent isolation of G4S-based CAR-T, CAR-NK, or CAR-M cells.
In Vitro Functional Assays: Preparation of highly purified CAR+ populations for activation, expansion, and functional screening.
Translational Process Quality Control: Direct assessment and sorting of CAR+ yields within manufacturing processes.
Labeling Type Direct
Bead Type Non-releasable
Format Column-based
Key feature

Excellent Column Compatibility: Seamlessly compatible with standard high-gradient magnetic columns, ensuring high recovery rates with minimal non-specific binding.
Minimal Steric Hindrance: 50 nm sized particles prevent receptor cross-linking or steric blockades of target antigen-binding sites.
Non-Destructive Technology: Biocompatible matrix ensures cells remain highly viable, fully functional, and ready for downstream cultivation.
Storage Store at 2°C-8°C