SOLIDEX®-ISOEx Anti-G4S Linker Nanobeads (Column-Based) (Cat No.:GMLS-Tag003-Ab01-nanoIMB)
Paramagnetic 50 nm nanobeads directly conjugated with a highly specific monoclonal antibody targeting the classic (GGGGS)n flexible linker (G4S linker) within the single-chain variable fragment (scFv) of CAR constructs. Designed for the high-purity, column-based magnetic enrichment or depletion of G4S-containing CAR-expressing immune cells.
Check GeneMedi's SOLIDEX™-ISOEx Cell Isolation Kit & Nanobeads
Order information
| Catalog No. | Product Name | Size | Price(In USD) |
|---|---|---|---|
| GMLS-Tag003-Ab01-nanoIMB-0.5mL | SOLIDEX®-ISOEx Anti-G4S Linker Nanobeads (Column-Based) | 0.5 mL | |
| GMLS-Tag003-Ab01-nanoIMB-1mL | SOLIDEX®-ISOEx Anti-G4S Linker Nanobeads (Column-Based) | 1 mL |
Description
| Cat No. | GMLS-Tag003-Ab01-nanoIMB |
| Product Name | SOLIDEX®-ISOEx Anti-G4S Linker Nanobeads (Column-Based) |
| Description | Paramagnetic 50 nm nanobeads directly conjugated with a highly specific monoclonal antibody targeting the classic (GGGGS)n flexible linker (G4S linker) within the single-chain variable fragment (scFv) of CAR constructs. Designed for the high-purity, column-based magnetic enrichment or depletion of G4S-containing CAR-expressing immune cells. |
| Application | Universal CAR Cell Enrichment: Direct, antigen-independent isolation of G4S-based CAR-T, CAR-NK, or CAR-M cells. In Vitro Functional Assays: Preparation of highly purified CAR+ populations for activation, expansion, and functional screening. Translational Process Quality Control: Direct assessment and sorting of CAR+ yields within manufacturing processes. |
| Component for 5E8 cells (50Tests) / 1E9 cells(100tests) / 7.5E9 cells (750tests) | GMLS-Tag003-Ab01-nanoIMB: SOLIDEX®-ISOEx Anti-G4S Linker Nanobeads (Column-Based) |
| Labeling Type | Direct |
| Bead Type | Non-releasable |
| Format | Column-based |
| Key feature | Excellent Column Compatibility: Seamlessly compatible with standard high-gradient magnetic columns, ensuring high recovery rates with minimal non-specific binding. Minimal Steric Hindrance: 50 nm sized particles prevent receptor cross-linking or steric blockades of target antigen-binding sites. Non-Destructive Technology: Biocompatible matrix ensures cells remain highly viable, fully functional, and ready for downstream cultivation. |
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