SOLIDEX®-ISOEx Streptavidin Nanobeads (Column-free) (Cat No.:GMLS-Tag004-nanoIMB-CF)

SOLIDEX®-ISOEx Streptavidin Nanobeads (Column-free) are part of GeneMedi's Universal Nanobeads family, designed for rapid and flexible cell isolation without the need for columns. These uniform, superparamagnetic nanoparticles are densely coated with high-activity recombinant streptavidin, enabling them to bind any biotinylated antibody or ligand with exceptional affinity and specificity. Simply incubate your cells with a biotinylated antibody of choice, followed by these nanobeads, and separate the labeled cells using a standard magnetic Sorter (e.g., SOLIDEX®-ISOEx Magnetic Sorter). The column-free workflow significantly reduces hands-on time and preserves cell viability, making it ideal for both routine and sensitive downstream applications.

Features

  • Column-free, Fast Protocol: Isolate cells in as little as 15 minutes without columns or complex equipment.

  • High-Affinity Streptavidin Coating: Tight biotin-streptavidin interaction ensures efficient, stable labeling with minimal non-specific binding.

  • Universal Compatibility: Works with any biotinylated primary antibody, ligand, or staining reagent; no need for dedicated antibody-conjugated beads.

  • Excellent Purity, Recovery & Viability: Achieve high purity and yield while maintaining cell functionality and surface marker integrity.

  • Flexible Selection Modes: Supports both positive selection (enrichment) and depletion (untouched isolation).

  • Scalable: Easily adapt protocols for sample sizes ranging from 10⁶ to 10⁸ total cells.


SOLIDEX®-ISOEx Streptavidin Nanobeads (Column-free) are superparamagnetic nanobeads covalently conjugated with high-affinity Streptavidin, designed for the gentle, column-free enrichment or depletion of cells pre-labeled with one or more biotinylated antibodies. Target cells are captured and separated directly on a magnetic stand or separator without a sorting column, minimizing operation time and cell loss. The optimized nanobead design preserves cell viability and function, delivering high purity and an economical workflow suitable for immune cell therapy, stem cell research, and functional cell analysis.
Check GeneMedi's SOLIDEX™-ISOEx Cell Isolation Kit & Nanobeads


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Order information


Catalog No. Product Name Size Price(In USD)
GMLS-Tag004-nanoIMB-CF-0.5mL SOLIDEX®-ISOEx Streptavidin Nanobeads (Column-free) 0.5 mL
GMLS-Tag004-nanoIMB-CF-1mL SOLIDEX®-ISOEx Streptavidin Nanobeads (Column-free) 1 mL

Description


Cat No. GMLS-Tag004-nanoIMB-CF
Product Name SOLIDEX®-ISOEx Streptavidin Nanobeads (Column-free)
Description SOLIDEX®-ISOEx Streptavidin Nanobeads (Column-free) are superparamagnetic nanobeads covalently conjugated with high-affinity Streptavidin, designed for the gentle, column-free enrichment or depletion of cells pre-labeled with one or more biotinylated antibodies. Target cells are captured and separated directly on a magnetic stand or separator without a sorting column, minimizing operation time and cell loss. The optimized nanobead design preserves cell viability and function, delivering high purity and an economical workflow suitable for immune cell therapy, stem cell research, and functional cell analysis.
Application Positive Selection (Enrichment): High-purity capture of biotinylated-antibody-labeled target cells (e.g., CD3+ T cells) from heterogeneous samples such as human PBMCs. Negative Selection / Depletion: Efficient removal of unwanted biotinylated-antibody-labeled cells during cell manufacturing workflows. High-Throughput & Small-Scale Workflows: The column-free design supports both small-scale experiments and high-throughput processing with minimal equipment.
Labeling Type Indirect
Bead Type Non-releasable
Format Column-free
Key feature Streptavidin–Biotin Capture: Ultra-high-affinity Streptavidin binding enables labeling with multiple biotinylated antibodies for flexible target recognition. Fast & Simple: Fewer steps than column-based methods, suitable for high-throughput workflows. Gentle on Cells: Reduces mechanical stress, preserving cell viability and function. Minimal Equipment: Requires only a magnetic stand or separation rack — no sorting column needed.
Cell population Biotinylated antibody-labeled cells
Storage Store at 2°C-8°C

Application

  • Enrichment or Depletion of Immune Cells: T cells, B cells, NK cells, monocytes, dendritic cells, and more from PBMCs, splenocytes, lymph node cells, and whole blood.
  • Rare Cell Population Isolation: Isolation of rare cell populations (e.g., regulatory T cells, antigen-specific cells) using custom biotinylated antibodies.
  • Positive Selection for Downstream Assays: Enrich target cells for cell culture, activation, or functional studies.
  • Negative Selection (Depletion): Depletion of unwanted cell types for untouched downstream analysis.