IFN-γ antibody and antigen (recombinant protein)

Diagnostic anti-IFN-γ antibodies pairs and antigen for animal health (animal Bovines/Cattle tuberculosis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Ruminants disease testing products collection >>


Product information

Catalog No. Description US $ Price (per mg)
GMP-BOV-IFN-y-Ag01 IFN-γ $3090.00
GMP-BOV-IFN-y-Ab01 Anti-IFN-γ mouse monoclonal antibody (mAb) $3090.00
GMP-BOV-IFN-y-Ab02 Anti-IFN-γ mouse monoclonal antibody (mAb) $3090.00
GMP-BOV-IFN-y-Ab03 Anti-IFN-γ human monoclonal antibody (mAb) $3090.00
GMP-BOV-IFN-y-Ab04 Anti-IFN-γ human monoclonal antibody (mAb) $3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-BOV-IFN-y-Ag01
Product Name IFN-γ
Target/Biomarker not infectious
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-IFN-γ antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in IFN-γ level test of animal Bovines/Cattle with tuberculosis.
Tag His
Reconized/Reactive Specics IFN-γ
Product description Recombinant IFN-γ protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-BOV-IFN-y-Ab01,GMP-BOV-IFN-y-Ab02
Target/Biomarker not infectious
Product Name Anti-IFN-γ mouse monoclonal antibody (mAb)
Expression platform Hybridoma
Isotypes Mouse IgG
Bioactivity validation Recombinant IFN-γ antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-IFN-γ antibodies in IFN-γ level test of animal Bovines/Cattle with tuberculosis.
Product description Anti-IFN-γ mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-IFN-γ antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-BOV-IFN-y-Ab03,GMP-BOV-IFN-y-Ab04
Target/Biomarker not infectious
Product Name Anti-IFN-γ human monoclonal antibody (mAb)
Expression platform CHO
Isotypes Human lgG1
Bioactivity validation Recombinant IFN-γ antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-IFN-γ antibodies in IFN-γ level test of animal Bovines/Cattle with tuberculosis.
Product description Anti-IFN-γ mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    IFNγ, or Interferon-gamma, is a versatile and indispensable biomarker within the context of cattle (bovines). This cytokine plays a central role in the bovine immune system's response to inflammatory challenges, particularly those posed by viral infections and intracellular pathogens. Produced by immune cells such as T cells, natural killer cells, and antigen-presenting cells, IFNγ serves as a linchpin in the immune defense of cattle.

    Structurally, IFNγ is a small protein that exerts its effects by binding to specific cell surface receptors. Upon binding, it initiates a complex signaling cascade that culminates in the activation of various immune effector functions. In the bovine immune system, IFNγ's primary function is to activate macrophages, enhancing their ability to recognize, engulf, and eliminate infected cells. This immune cascade is a critical component of the host's defense against viral infections and other intracellular pathogens.

    The measurement of IFNγ in cattle transcends routine biomarker assessment; it represents a cornerstone of bovine healthcare and scientific inquiry. The multifaceted significance of IFNγ encompasses various aspects of veterinary medicine and research.

    Firstly, IFNγ serves as a sentinel of infection in cattle. Its rapid production and release in response to pathogens, particularly viruses, position it as a crucial diagnostic tool for veterinarians. Elevated IFNγ levels can indicate the presence of intracellular infections, offering valuable insights into the specific pathogens responsible for the disease. This information is instrumental in implementing targeted treatment strategies, antiviral therapies, and vaccination protocols.

    Secondly, IFNγ monitoring plays a pivotal role in assessing the effectiveness of antiviral treatments and vaccines in cattle. By quantifying changes in IFNγ levels over the course of treatment or vaccination, veterinarians can gauge the response of the immune system. This dynamic monitoring enables timely adjustments to treatment plans and vaccination strategies, ultimately improving the management of infectious diseases in bovines.

    Beyond its diagnostic and therapeutic applications, IFNγ serves as a bridge between clinical veterinary practice and scientific research in cattle. Ongoing investigations into IFNγ dynamics in different disease contexts expand our understanding of bovine immunology and the intricate interplay between the immune response and infectious agents. These studies not only contribute to the advancement of bovine healthcare but also facilitate the development of innovative diagnostic tools, therapeutic interventions, and vaccination strategies.

    In conclusion, IFNγ in cattle is more than a biomarker; it is a sentinel of infection, a linchpin in disease management, and a conduit for scientific exploration. The measurement of IFNγ in bovines embodies the fusion of clinical veterinary expertise and cutting-edge scientific inquiry, ultimately promoting the health and well-being of cattle populations worldwide.



    About GDU


    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.