Equine MOG antibody and antigen (recombinant protein)

Diagnostic anti-Equine MOG antibodies pairs and antigen for animal health (animal Equine/Horse MOG antibody disease) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Equine disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-EQU-MOG-Ag01Equine MOG$3090.00
GMP-EQU-MOG-Ab01Anti-Equine MOG mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-MOG-Ab02Anti-Equine MOG mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-MOG-Ab03Anti-Equine MOG human monoclonal antibody (mAb)$3090.00
GMP-EQU-MOG-Ab04Anti-Equine MOG human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-EQU-MOG-Ag01
Product NameEquine MOG
Target/BiomarkerEquine MOG
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Equine MOG antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in MOG level test of animal Equine/Horse with MOG antibody disease.
TagHis
Reconized/Reactive SpecicsEquine MOG
Product descriptionRecombinant Equine MOG protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-MOG-Ab01,GMP-EQU-MOG-Ab02
Target/BiomarkerEquine MOG
Product NameAnti-Equine MOG mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Equine MOG antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine MOG antibodies in Equine MOG level test of animal Equine/Horse with MOG antibody disease.
Product descriptionAnti-Equine MOG mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine MOG antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-MOG-Ab03,GMP-EQU-MOG-Ab04
Target/BiomarkerEquine MOG
Product NameAnti-Equine MOG human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Equine MOG antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine MOG antibodies in Equine MOG level test of animal Equine/Horse with MOG antibody disease.
Product descriptionAnti-Equine MOG mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Myelin Oligodendrocyte Glycoprotein (MOG) in horses represents a pivotal component of the central nervous system (CNS), where its role in maintaining the integrity of the myelin sheath and its potential involvement in immune regulation within the CNS have garnered significant scientific interest.

    MOG is a glycoprotein primarily localized on the surface of oligodendrocytes, specialized glial cells tasked with the production of the myelin sheath. This sheath serves as an insulating layer around nerve fibers, enabling efficient conduction of electrical signals along neurons. MOG's presence on oligodendrocytes is essential for the adhesion between the myelin sheath and the underlying axons, ensuring structural stability and the preservation of nerve function.

    Within the context of the immune system, MOG's role is multifaceted and not fully elucidated. It is believed to participate in immune regulation within the CNS, contributing to the maintenance of immune tolerance. However, under certain conditions, such as autoimmune responses, MOG can become a target of the immune system, leading to the production of autoantibodies against MOG.

    In horses, as in other vertebrates, MOG is critical for the normal functioning of the CNS. Its role in facilitating rapid nerve signal transmission and its involvement in immune processes highlight its significance in equine neurological health.



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