Equine pancreatic lipase antibody and antigen (recombinant protein)

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Diagnostic anti-Equine pancreatic lipase antibodies pairs and antigen for animal health (animal Equine/Horse Pancreatitis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Size： 1mg | 10mg | 100mg

Product Description

Reference

Validation Data

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Target/Biomarker Information

Pancreatic lipase in horses is an enzyme produced by the pancreas that plays a crucial role in the digestion of dietary fats. It works specifically in the small intestine to hydrolyze triglycerides, which are the main form of dietary fats, into monoglycerides and free fatty acids. These products are then absorbed by the cells lining the intestinal tract and used by the body.

Functions and Importance of Equine Pancreatic Lipase:

Digestion of Fats: Pancreatic lipase is key to the efficient breakdown of triglycerides into absorbable units. Without this enzyme, fats would pass through the digestive system largely unprocessed, leading to fat deficiencies and malabsorption syndromes.

Energy Source: The free fatty acids produced by the action of lipase serve as an important source of energy for horses. For performance horses, fat can provide a more concentrated source of energy compared to carbohydrates.

Nutrient Absorption: The digestion of fats also enables the absorption of fat-soluble vitamins (A, D, E, and K) which are crucial for various bodily functions, including vision, blood clotting, and maintaining healthy skin and mucous membranes.

Clinical Aspects and Applications:

Exocrine Pancreatic Insufficiency (EPI): If the pancreas fails to produce adequate levels of pancreatic lipase, it can lead to EPI. While rare in horses, EPI can result in malabsorption, weight loss, and a dull coat due to the inability to properly digest and absorb fats.

Diagnosis of Pancreatic Disorders: Measurement of pancreatic lipase can be used as a diagnostic tool in horses suspected of having pancreatic dysfunction. Elevated levels of lipase in the blood can indicate pancreatic inflammation or damage, although this is less commonly seen in equine practice compared to small animal practice.

Lipase Supplements: In other animals, pancreatic enzyme supplements can be used to treat EPI, and while not common, they could theoretically be used in horses if necessary.

Dietary Management:

Horses typically do not have high-fat diets, but the introduction of dietary fats can be a strategy for providing high-energy feed to performance horses. Ensuring that pancreatic lipase function is optimal is necessary for the efficient use of these fats.

In cases where pancreatic function is compromised, dietary management may need to be adjusted to ensure that the horse can still meet its nutritional requirements.

In summary, equine pancreatic lipase is essential for the digestion and absorption of dietary fats in horses. It is involved in critical processes that contribute to the overall energy metabolism and nutritional health of the horse. While issues with pancreatic lipase are not commonly diagnosed in equine medicine, it remains an important enzyme for digestive health and energy balance.

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