feline pancreatic lipase antibody and antigen (recombinant protein)

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Diagnostic anti-feline pancreatic lipase antibodies pairs and antigen for animal health (animal Cat/Feline pancreatitis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-FEL-Pancreatic-lipase-Ag01	feline pancreatic lipase	$3090.00
GMP-FEL-Pancreatic-lipase-Ab01	Anti-feline pancreatic lipase mouse monoclonal antibody (mAb)	$3090.00
GMP-FEL-Pancreatic-lipase-Ab02	Anti-feline pancreatic lipase mouse monoclonal antibody (mAb)	$3090.00
GMP-FEL-Pancreatic-lipase-Ab03	Anti-feline pancreatic lipase human monoclonal antibody (mAb)	$3090.00
GMP-FEL-Pancreatic-lipase-Ab04	Anti-feline pancreatic lipase human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-FEL-Pancreatic-lipase-Ag01
Product Name	feline pancreatic lipase
Target/Biomarker	not infectious
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-feline pancreatic lipase antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in feline pancreatic lipase level test of animal Cat/Feline with pancreatitis.
Tag	His
Reconized/Reactive Specics	feline pancreatic lipase
Product description	Recombinant feline pancreatic lipase protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-FEL-Pancreatic-lipase-Ab01,GMP-FEL-Pancreatic-lipase-Ab02
Target/Biomarker	not infectious
Product Name	Anti-feline pancreatic lipase mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant feline pancreatic lipase antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-feline pancreatic lipase antibodies in feline pancreatic lipase level test of animal Cat/Feline with pancreatitis.
Product description	Anti-feline pancreatic lipase mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-feline pancreatic lipase antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-FEL-Pancreatic-lipase-Ab03,GMP-FEL-Pancreatic-lipase-Ab04
Target/Biomarker	not infectious
Product Name	Anti-feline pancreatic lipase human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant feline pancreatic lipase antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-feline pancreatic lipase antibodies in feline pancreatic lipase level test of animal Cat/Feline with pancreatitis.
Product description	Anti-feline pancreatic lipase mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker Information

The measurement of Feline Pancreatic Lipase (fPL) levels is a cornerstone of veterinary diagnostics, bearing profound implications for the detection, management, and understanding of pancreatitis in cats. Pancreatitis, characterized by inflammation of the pancreas, is a relatively common yet challenging condition in feline medicine. Its timely diagnosis and appropriate management are vital for the well-being of affected cats.

Elevated fPL levels in the blood or serum serve as a sentinel, signaling the presence of pancreatitis. This phenomenon arises from the leakage of digestive enzymes, including fPL, into the bloodstream as a consequence of pancreatic cell damage or inflammation. The measurement of fPL levels is a reliable diagnostic tool, facilitating the early detection of pancreatitis in cats.

Beyond its diagnostic utility, fPL measurement aids in the assessment of the severity of pancreatitis. Differentiating between mild, moderate, and severe cases is critical for tailoring treatment strategies. For instance, severe pancreatitis may necessitate aggressive interventions, such as hospitalization and intravenous fluids, whereas mild cases may be managed on an outpatient basis.

Furthermore, serial measurements of fPL levels provide a dynamic view of the disease's progression and the response to treatment. This allows veterinarians to adapt therapeutic regimens based on the individual cat's response, optimizing care and improving outcomes. It also helps in assessing the resolution of pancreatitis, providing a clearer picture of when a cat has recovered from the condition.

Importantly, fPL measurement aids in distinguishing pancreatitis from other gastrointestinal disorders with overlapping clinical symptoms, such as inflammatory bowel disease (IBD). Accurate differentiation is critical for selecting the most appropriate treatments and ensuring the best possible outcome for affected cats. Misdiagnosis or delayed diagnosis can lead to suboptimal care and potentially worsen the cat's condition.

From a research perspective, fPL measurement contributes to a deeper understanding of pancreatitis's pathophysiology and its impact on feline health. Ongoing research endeavors seek to elucidate the underlying mechanisms of pancreatitis, identify risk factors, and develop novel treatments. fPL measurements are a valuable tool in these investigations, providing quantitative data that can be analyzed to enhance our knowledge of this complex disease.

In summary, the measurement of Feline Pancreatic Lipase (fPL) is not just a diagnostic test; it is a linchpin in the diagnosis, management, and research of pancreatitis in cats. Its clinical utility extends from early detection to treatment monitoring and enhances our understanding of feline health and disease. By quantifying fPL levels, veterinarians and researchers can provide better care for our feline companions and advance the frontiers of feline medicine., Feline Pancreatic Lipase (fPL) is an enzymatic linchpin in the intricate process of dietary fat digestion within the feline digestive system. Structurally, fPL is a member of the pancreatic lipase family and bears a high degree of homology to lipases found in other species. Its functional significance lies in its ability to hydrolyze triglycerides, the primary form of dietary fats, into glycerol and fatty acids, rendering them absorbable by the feline body.

The production of fPL occurs predominantly in the exocrine pancreas, where it is synthesized and subsequently secreted into the small intestine. Upon reaching the duodenum, fPL comes into play, catalyzing the cleavage of triglycerides into their constituent components. This enzymatic reaction is a fundamental step in lipid metabolism, as it prepares fats for absorption across the intestinal wall.

Fats, in the form of fatty acids and glycerol, are indispensable nutrients for cats, serving as a dense energy source and contributing to various physiological processes, including the formation of cell membranes and the absorption of fat-soluble vitamins. The efficiency of this process relies heavily on the activity and availability of fPL.

Moreover, fPL's role extends beyond simple digestion. Its proper functioning is essential for the overall well-being and nutritional health of cats. Any perturbation in fPL activity can have far-reaching consequences, potentially impacting a cat's ability to utilize dietary fats, resulting in nutrient deficiencies and metabolic imbalances.

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