Chlamydiaceae ompA antibody and antigen (recombinant protein)

Diagnostic anti-Chlamydiaceae ompA antibodies pairs and antigen for animal health (animal Avian/Bird/Poultry infectious disease Chlamydia) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Avian/Bird/Poultry disease testing products collection >>


Product information

Catalog No. Description US $ Price (per mg)
GMP-VT-P046-Tg003-Ag01 Recombinant Chlamydiaceae ompA protein $3090.00
GMP-VT-P046-Tg003-Ab01 Anti-Chlamydiaceae ompA mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P046-Tg003-Ab02 Anti-Chlamydiaceae ompA mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P046-Tg003-Ab03 Anti-Chlamydiaceae ompA human monoclonal antibody (mAb) $3090.00
GMP-VT-P046-Tg003-Ab04 Anti-Chlamydiaceae ompA human monoclonal antibody (mAb) $3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-VT-P046-Tg003-Ag01
Product Name Recombinant Chlamydiaceae ompA protein
Pathogen Chlamydiaceae
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Chlamydiaceae ompA antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Chlamydiaceae level test of animal Avian/Bird/Poultry infectious disease with Chlamydia.
Tag His
Product description Recombinant Chlamydiaceae ompA proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P046-Tg003-Ab01,GMP-VT-P046-Tg003-Ab02
Pathogen Chlamydiaceae
Product Name Anti-Chlamydiaceae ompA mouse monoclonal antibody (mAb)
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Recombinant Chlamydiaceae ompA antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Chlamydiaceae antibodies in Chlamydiaceae level test of animal Avian/Bird/Poultry infectious disease with Chlamydia.
Product description Anti-Chlamydiaceae ompA mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Chlamydiaceae antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P046-Tg003-Ab03,GMP-VT-P046-Tg003-Ab04
Pathogen Chlamydiaceae
Product Name Anti-Chlamydiaceae ompA human monoclonal antibody (mAb)
Expression platform CHO
Isotypes Human lgG1
Bioactivity validation Recombinant Chlamydiaceae ompA antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Chlamydiaceae antibodies in Chlamydiaceae level test of animal Avian/Bird/Poultry infectious disease with Chlamydia.
Product description Anti-Chlamydiaceae ompA mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Pathogen Information


    Swine Chlamydiaceae, also referred to as Porcine or Pig Chlamydiaceae, are a group of obligate intracellular pathogens belonging to the family Chlamydiaceae. This family includes various species that can infect a wide range of hosts, including pigs (Sus scrofa), humans, and other animals. In this expanded description, we will delve into the characteristics, host interactions, associated diseases, diagnostic methods, and potential treatments related to Swine Chlamydiaceae.

    Chlamydiaceae is a group of Gram-negative bacteria that exhibit a unique biphasic developmental cycle. This cycle consists of two distinct forms: the infectious elementary body (EB) and the non-infectious reticulate body (RB). The EB is the extracellular form responsible for transmission between hosts, while the RB is the intracellular form that replicates within host cells. Swine Chlamydiaceae possess an outer membrane protein A (ompA) gene, which encodes an essential protein involved in host cell attachment and entry. This protein is a major target for developing vaccines and diagnostic assays.

    Pigs serve as important reservoir hosts for Swine Chlamydiaceae. Upon infection, these bacteria can cause various clinical manifestations collectively known as porcine chlamydiosis. The respiratory form of the disease is characterized by coughing, nasal discharge, and difficulty breathing. Reproductive disorders may include infertility, abortion, stillbirths, and weak piglets. Conjunctivitis, often referred to as pink eye, is another common symptom observed in infected pigs. Additionally, zoonotic infections can occur, where humans may acquire Swine Chlamydiaceae through direct contact with infected animals or their secretions. In humans, these infections can lead to respiratory illnesses such as pneumonia and psittacosis.

    Accurate and timely diagnosis of Swine Chlamydiaceae infection is vital for effective disease management. Several diagnostic methods are available, including serological tests, antigen detection assays, and nucleic acid amplification tests (NAATs) such as polymerase chain reaction (PCR). Serological tests detect the presence of antibodies specific to Swine Chlamydiaceae in the host's blood serum. Antigen detection assays, on the other hand, detect pathogen-specific proteins in clinical samples. NAATs, particularly PCR, allow for the direct detection and amplification of Swine Chlamydiaceae DNA, providing a highly sensitive and specific diagnostic tool.

    Treatment options for Swine Chlamydiaceae infections are limited. Antibiotics such as tetracyclines and macrolides have shown efficacy in reducing the severity of clinical signs and shedding of the bacteria. However, it is crucial to adhere to proper dosage and withdrawal periods to avoid antimicrobial resistance and residues in food products.

    Prevention and control strategies for Swine Chlamydiaceae primarily focus on biosecurity measures, vaccination, and herd management practices. Strict hygiene protocols, proper quarantine procedures, and maintaining a closed herd system can help minimize the risk of introduction and spread of the pathogen. Vaccination plays an essential role in reducing the incidence and severity of chlamydial infections in pigs. Development of vaccines targeting key proteins like ompA and MOMP (major outer membrane protein) is an active area of research.

    In conclusion, Swine Chlamydiaceae are a group of intracellular pathogens that can infect pigs, humans, and other animals. Their unique biphasic developmental cycle, coupled with the ability to cause respiratory disease, reproductive disorders, and conjunctivitis in pigs, necessitates accurate diagnosis and effective control measures. The development of diagnostic techniques and potential vaccines holds promise for managing and mitigating the impact of Swine Chlamydiaceae infections in both animal and human populations.



    About GDU


    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.